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创伤后应激障碍住院患者噩梦主诉的实验室睡眠相关因素

Laboratory sleep correlates of nightmare complaint in PTSD inpatients.

作者信息

Woodward S H, Arsenault N J, Murray C, Bliwise D L

机构信息

National Center for PTSD, Clinical Laboratory and Education Division, Veterans Administration Palo Alto Health Care System, Palo Alto, California, USA.

出版信息

Biol Psychiatry. 2000 Dec 1;48(11):1081-7. doi: 10.1016/s0006-3223(00)00917-3.

DOI:10.1016/s0006-3223(00)00917-3
PMID:11094141
Abstract

BACKGROUND

Nightmares are rare in the sleep laboratory, even in patients with posttraumatic stress disorder for whom nightmare complaints are diagnostic. Nevertheless, it is possible that laboratory conditions do not preclude the observation of telltales-nightmare-related modifications of tonic sleep-given sufficiently large samples.

METHODS

Sixty-three unmedicated, nonapneic Vietnam combat veterans undergoing inpatient treatment for posttraumatic stress disorder underwent polysomnographic testing and assessment of nightmare complaint.

RESULTS

Trauma-related nightmare complaint, but not non-trauma-related complaint, was associated with increased wake-after-sleep-onset in the sleep laboratory. No relationships between nightmare complaint and rapid eye movement sleep architecture were observed.

CONCLUSIONS

Increased wake-after-sleep-onset was specifically associated with trauma-related nightmare complaint, confirming data from other quarters suggesting they are both phenomenologically and functionally distinct from normal dreaming.

摘要

背景

噩梦在睡眠实验室中很少见,即使在创伤后应激障碍患者中也是如此,而噩梦主诉对该疾病具有诊断意义。然而,在样本量足够大的情况下,实验室条件并不排除观察到与噩梦相关的、静息睡眠的特征性改变。

方法

63名未接受药物治疗、无呼吸暂停的越战退伍军人因创伤后应激障碍正在接受住院治疗,他们接受了多导睡眠图测试和噩梦主诉评估。

结果

在睡眠实验室中,与创伤相关的噩梦主诉而非与创伤无关的主诉与睡眠起始后觉醒增加有关。未观察到噩梦主诉与快速眼动睡眠结构之间的关系。

结论

睡眠起始后觉醒增加与创伤相关的噩梦主诉有特定关联,这证实了其他研究的数据,表明它们在现象学和功能上均与正常梦境不同。

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