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家庭医疗中的轻度抑郁症:功能损害、共病、服务利用及结局

Minor depression in family practice: functional morbidity, co-morbidity, service utilization and outcomes.

作者信息

Wagner H R, Burns B J, Broadhead W E, Yarnall K S, Sigmon A, Gaynes B N

机构信息

Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.

出版信息

Psychol Med. 2000 Nov;30(6):1377-90. doi: 10.1017/s0033291799002998.

DOI:10.1017/s0033291799002998
PMID:11097078
Abstract

BACKGROUND

Minor depression is a disabling condition commonly seen in primary care settings. Although considerable impairment is associated with minor depression, little is known about the course of the illness. Using a variety of clinical and functional measurements, this paper profiles the course of minor depression over a 1 year interval among a cohort of primary care patients.

METHOD

Patients at a university-based primary care facility were screened for potential cases of depression and selected into three diagnostic categories: an asymptomatic control group; patients with a diagnosis of major depression; and, a third category, defined as minor depression, consisting of patients who reported between two and four symptoms of depression, but who failed to qualify for a diagnosis of major depression. Functional status, service use, and physical, social and mental health were assessed at baseline and at 3-month intervals for the ensuing year.

RESULTS

Respondents with a baseline diagnosis of minor depression exhibited marked impairment on most measures both at baseline and over the following four waves. Their responses in most respects were similar to, although not as severe as, those of respondents with a baseline diagnosis of major depression. Both groups were considerably more impaired than asymptomatic controls.

CONCLUSIONS

Minor depression is a persistently disabling condition often seen in primary care settings. Although quantitatively less severe than major depression, it is qualitatively similar and requires careful assessment and close monitoring over the course of the illness.

摘要

背景

轻度抑郁症是一种在初级保健机构中常见的致残性疾病。尽管轻度抑郁症会导致相当大的功能损害,但人们对该疾病的病程了解甚少。本文通过各种临床和功能测量方法,描绘了一组初级保健患者在1年时间内轻度抑郁症的病程。

方法

在一家大学附属的初级保健机构对患者进行抑郁症潜在病例筛查,并分为三个诊断类别:无症状对照组;被诊断为重度抑郁症的患者;以及第三类,定义为轻度抑郁症,包括报告有两到四种抑郁症状但不符合重度抑郁症诊断标准的患者。在基线时以及随后一年中每3个月对功能状态、服务使用情况以及身体、社会和心理健康状况进行评估。

结果

基线诊断为轻度抑郁症的受访者在基线时以及随后的四次评估中,在大多数测量指标上都表现出明显的功能损害。他们在大多数方面的反应与基线诊断为重度抑郁症的受访者相似,尽管程度没有那么严重。两组的功能损害程度都明显高于无症状对照组。

结论

轻度抑郁症是一种在初级保健机构中经常出现的持续性致残性疾病。虽然在数量上不如重度抑郁症严重,但在性质上相似,需要在疾病过程中进行仔细评估和密切监测。

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