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本文引用的文献

1
Macrolide resistance.大环内酯类耐药性
Drug Resist Updat. 1998 Mar;1(1):29-41. doi: 10.1016/s1368-7646(98)80212-4.
2
The tylosin resistance gene tlrB of Streptomyces fradiae encodes a methyltransferase that targets G748 in 23S rRNA.弗氏链霉菌的泰乐菌素抗性基因tlrB编码一种靶向23S rRNA中G748的甲基转移酶。
Mol Microbiol. 2000 Aug;37(4):811-20. doi: 10.1046/j.1365-2958.2000.02046.x.
3
Mutations in 23S rRNA and ribosomal protein L4 account for resistance in pneumococcal strains selected in vitro by macrolide passage.23S核糖体RNA和核糖体蛋白L4中的突变导致了在体外经大环内酯类药物传代筛选出的肺炎球菌菌株产生耐药性。
Antimicrob Agents Chemother. 2000 Aug;44(8):2118-25. doi: 10.1128/AAC.44.8.2118-2125.2000.
4
Studies of the novel ketolide ABT-773: transport, binding to ribosomes, and inhibition of protein synthesis in Streptococcus pneumoniae.新型酮内酯ABT-773的研究：转运、与核糖体的结合以及对肺炎链球菌蛋白质合成的抑制作用
Antimicrob Agents Chemother. 2000 Jun;44(6):1562-7. doi: 10.1128/AAC.44.6.1562-1567.2000.
5
Macrolide-ketolide inhibition of MLS-resistant ribosomes is improved by alternative drug interaction with domain II of 23S rRNA.通过与23S rRNA的结构域II进行替代性药物相互作用，可增强大环内酯-酮内酯对MLS耐药核糖体的抑制作用。
Mol Microbiol. 2000 Apr;36(1):183-93. doi: 10.1046/j.1365-2958.2000.01841.x.
6
The 3D arrangement of the 23 S and 5 S rRNA in the Escherichia coli 50 S ribosomal subunit based on a cryo-electron microscopic reconstruction at 7.5 A resolution.基于7.5埃分辨率的冷冻电子显微镜重建，大肠杆菌50S核糖体亚基中23S和5S rRNA的三维排列。
J Mol Biol. 2000 Apr 21;298(1):35-59. doi: 10.1006/jmbi.2000.3635.
7
Nomenclature for macrolide and macrolide-lincosamide-streptogramin B resistance determinants.大环内酯类及大环内酯-林可酰胺-链阳菌素B耐药决定簇的命名法。
Antimicrob Agents Chemother. 1999 Dec;43(12):2823-30. doi: 10.1128/AAC.43.12.2823.
8
The biological cost of antibiotic resistance.抗生素耐药性的生物学代价。
Curr Opin Microbiol. 1999 Oct;2(5):489-93. doi: 10.1016/s1369-5274(99)00005-3.
9
X-ray crystal structures of 70S ribosome functional complexes.70S核糖体功能复合物的X射线晶体结构。
Science. 1999 Sep 24;285(5436):2095-104. doi: 10.1126/science.285.5436.2095.
10
Placement of protein and RNA structures into a 5 A-resolution map of the 50S ribosomal subunit.将蛋白质和RNA结构置于50S核糖体亚基的5埃分辨率图谱中。
Nature. 1999 Aug 26;400(6747):841-7. doi: 10.1038/23641.

Macrolide resistance conferred by base substitutions in 23S rRNA.

作者信息

Vester B, Douthwaite S

机构信息

Department of Molecular Biology, University of Copenhagen, DK-1307 Copenhagen K, Denmark.

出版信息

Antimicrob Agents Chemother. 2001 Jan;45(1):1-12. doi: 10.1128/AAC.45.1.1-12.2001.

DOI:10.1128/AAC.45.1.1-12.2001
PMID:11120937
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC90232/
Abstract
摘要