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术后超声引导下连续股神经阻滞用于单侧全膝关节置换术:0.125%布比卡因与0.2%罗哌卡因的比较

Postoperative Ultrasound Guided Continuous Femoral Nerve Blockade for Unilateral Total Knee Arthroplasty: A Comparison of 0.125% Bupivacaine and 0.2% Ropivacaine.

作者信息

Babu Sruthi C, Menon Gokuldas, Vasu Bindu K, George Mathew, Thilak Jai, Iyer Sundaram

机构信息

Department of Anaesthesia and Critical Care, Amrita Institute of Medical Sciences and Research Centre, Amrita University, Kochi, Kerala, India.

Department of Orthopaedics, Amrita Institute of Medical Sciences and Research Centre, Amrita University, Kochi, Kerala, India.

出版信息

Anesth Essays Res. 2017 Oct-Dec;11(4):1026-1029. doi: 10.4103/aer.AER_155_17.

DOI:10.4103/aer.AER_155_17
PMID:29284869
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5735444/
Abstract

CONTEXT

Total knee arthroplasty (TKA) is associated with severe postoperative pain which increases morbidity and mortality.

AIMS

The aim of the study was to compare the analgesic efficacy and motor blockade of continuous infusion of 0.125% bupivacaine and 0.2% ropivacaine in femoral nerve block following unilateral TKA and to assess the effectiveness of femoral nerve block.

SETTINGS AND DESIGN

One hundred and fifty patients undergoing unilateral total knee replacement surgery were included in this prospective observational comparative study.

SUBJECTS AND METHODS

Patients are divided into two groups of 75 each. Femoral nerve catheter was placed at the end of surgery using ultrasound. Postoperative analgesia and motor blockade were compared for the next 24 h using visual analog scale (VAS) score, additional analgesic requirement, and Bromage scale.

STATISTICAL ANALYSIS

Student's -test and Chi-square test were applied.

RESULTS

There was no statistically significant difference in pain between the two groups though VAS score (during rest and movement) and opioid consumption were lower in bupivacaine group. Nearly 28.6% patients experienced pain and required additional analgesics. Seventy-two percent among them complained of pain in the popliteal region supplied by sciatic nerve. Eight patients excluded from the study also had pain in the popliteal fossa. There was a statistically significant difference in motor blockade between the two groups at 12, 18, and 24 h after starting infusion. Bupivacaine group had a higher percentage of type three blocks compared to ropivacaine group.

CONCLUSION

Continuous femoral nerve block (CFNB) with 0.125% bupivacaine infusion provided better analgesia with denser motor blockade compared to 0.2% ropivacaine infusion. CFNB alone is not sufficient to provide adequate analgesia following unilateral TKA.

摘要

背景

全膝关节置换术(TKA)与严重的术后疼痛相关,这会增加发病率和死亡率。

目的

本研究的目的是比较单侧TKA后股神经阻滞中持续输注0.125%布比卡因和0.2%罗哌卡因的镇痛效果和运动阻滞情况,并评估股神经阻滞的有效性。

设置与设计

本前瞻性观察性比较研究纳入了150例行单侧全膝关节置换手术的患者。

对象与方法

患者分为两组,每组75例。在手术结束时使用超声放置股神经导管。在接下来的24小时内,使用视觉模拟量表(VAS)评分、额外镇痛需求和布罗玛吉量表比较术后镇痛和运动阻滞情况。

统计分析

应用学生t检验和卡方检验。

结果

两组之间的疼痛无统计学显著差异,尽管布比卡因组的VAS评分(休息和活动时)和阿片类药物消耗量较低。近28.6%的患者经历疼痛并需要额外的镇痛药。其中72%的患者抱怨坐骨神经支配的腘窝区域疼痛。8例被排除在研究之外的患者腘窝也有疼痛。开始输注后12、18和24小时,两组之间的运动阻滞有统计学显著差异。与罗哌卡因组相比,布比卡因组三级阻滞的百分比更高。

结论

与输注0.2%罗哌卡因相比,输注0.125%布比卡因的持续股神经阻滞(CFNB)提供了更好的镇痛效果和更密集的运动阻滞。单独的CFNB不足以在单侧TKA后提供充分的镇痛。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88f0/5735444/fd13f396ea38/AER-11-1026-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88f0/5735444/58a2a69c8fda/AER-11-1026-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88f0/5735444/d44966e65704/AER-11-1026-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88f0/5735444/fb8c9d93bf73/AER-11-1026-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88f0/5735444/fd13f396ea38/AER-11-1026-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88f0/5735444/58a2a69c8fda/AER-11-1026-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88f0/5735444/d44966e65704/AER-11-1026-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88f0/5735444/fb8c9d93bf73/AER-11-1026-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88f0/5735444/fd13f396ea38/AER-11-1026-g007.jpg

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