Shore A C
Department of Diabetes and Vascular Medicine, School of Postgraduate Medicine and Health Sciences, University of Exeter, EX2 5AX.
Br J Clin Pharmacol. 2000 Dec;50(6):501-13. doi: 10.1046/j.1365-2125.2000.00278.x.
Capillaries play a critical role in cardiovascular function as the point of exchange of nutrients and waste products between the tissues and circulation. Studies of capillary function in man are limited by access to the vascular bed. However, skin capillaries can readily be studied by the technique of capillaroscopy which enables the investigator to assess morphology, density and blood flow velocity. It is also possible to estimate capillary pressure by direct cannulation using glass micropipettes. This review will describe the techniques used to make these assessments and will outline some of the changes that are seen in health and disease.
毛细血管在心血管功能中起着关键作用，它是组织与循环系统之间营养物质和代谢废物交换的场所。人体毛细血管功能的研究受到血管床获取途径的限制。然而，通过毛细血管镜检查技术可以很容易地研究皮肤毛细血管，该技术使研究人员能够评估其形态、密度和血流速度。使用玻璃微量移液器直接插管也可以估计毛细血管压力。本综述将描述用于进行这些评估的技术，并概述在健康和疾病状态下观察到的一些变化。
