采用肉汤稀释法比较伏立康唑与五种已确立的抗真菌药物对不同皮肤癣菌的体外活性。
Comparison of in vitro activities of voriconazole and five established antifungal agents against different species of dermatophytes using a broth macrodilution method.
作者信息
Perea S, Fothergill A W, Sutton D A, Rinaldi M G
机构信息
Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78284-7881, USA.
出版信息
J Clin Microbiol. 2001 Jan;39(1):385-8. doi: 10.1128/JCM.39.1.385-388.2001.
Abstract
The in vitro activities of voriconazole against 19 different species of dermatophytes were compared with those of terbinafine, itraconazole, ketoconazole, griseofulvin, and fluconazole. MICs were determined according to a National Committee for Clinical Laboratory Standards broth macrodilution method. Voriconazole appeared more active than ketoconazole, griseofulvin, and fluconazole and less active than itraconazole and terbinafine. Based on these results, voriconazole merits further investigation as a potentially useful agent for the treatment of dermatophytosis.
摘要
将伏立康唑对19种不同皮肤癣菌的体外活性与特比萘芬、伊曲康唑、酮康唑、灰黄霉素和氟康唑进行了比较。根据美国国家临床实验室标准委员会的肉汤稀释法测定最低抑菌浓度（MIC）。伏立康唑似乎比酮康唑、灰黄霉素和氟康唑更具活性，而比伊曲康唑和特比萘芬活性低。基于这些结果，伏立康唑作为治疗皮肤癣菌病的潜在有用药物值得进一步研究。
相似文献
1
Comparison of in vitro activities of voriconazole and five established antifungal agents against different species of dermatophytes using a broth macrodilution method.采用肉汤稀释法比较伏立康唑与五种已确立的抗真菌药物对不同皮肤癣菌的体外活性。
J Clin Microbiol. 2001 Jan;39(1):385-8. doi: 10.1128/JCM.39.1.385-388.2001.
2
In vitro activity of posaconazole against clinical isolates of dermatophytes.泊沙康唑对皮肤癣菌临床分离株的体外活性。
J Clin Microbiol. 2001 Nov;39(11):4208-9. doi: 10.1128/JCM.39.11.4208-4209.2001.
3
In vitro activity of fluconazole, itraconazole, voriconazole and terbinafine against fungi causing onychomycosis.体外抗真菌药物氟康唑、伊曲康唑、伏立康唑和特比萘芬治疗甲真菌病的活性。
Clin Exp Dermatol. 2010 Aug;35(6):658-63. doi: 10.1111/j.1365-2230.2009.03698.x. Epub 2009 Oct 23.
4
In vitro activity of voriconazole against yeasts, moulds and dermatophytes in comparison with fluconazole, amphotericin B and griseofulvin.伏立康唑与氟康唑、两性霉素B和灰黄霉素相比，对酵母、霉菌和皮肤癣菌的体外活性。
Arzneimittelforschung. 1997 Nov;47(11):1257-63.
5
Comparison of E-Test, disk diffusion and a modified CLSI broth microdilution (M 38-A) method for in vitro testing of itraconazole, fluconazole and voriconazole against dermatophytes.伊曲康唑、氟康唑和伏立康唑对皮肤癣菌体外药敏试验的E试验、纸片扩散法和改良的CLSI肉汤微量稀释法（M 38 - A）比较
Med Mycol. 2008 Mar;46(2):119-23. doi: 10.1080/13693780701670491.
6
Comparison of in vitro antifungal activity of novel triazoles with available antifungal agents against dermatophyte species caused tinea pedis.比较新型三氮唑类药物与现有抗真菌药物对引起足癣的皮肤癣菌的体外抗真菌活性。
J Mycol Med. 2020 Jun;30(2):100935. doi: 10.1016/j.mycmed.2020.100935. Epub 2020 Jan 30.
7
[In vitro antifungal activity of voriconazole against dermatophytes and superficial isolates of Scopulariopsis brevicaulis].伏立康唑对皮肤癣菌和短帚霉浅表分离株的体外抗真菌活性
Rev Iberoam Micol. 2005 Jun;22(2):110-3. doi: 10.1016/s1130-1406(05)70019-x.
8
In vitro activity of voriconazole against dermatophytes, Scopulariopsis brevicaulis and other opportunistic fungi as agents of onychomycosis.伏立康唑对皮肤癣菌、短帚霉及其他引起甲真菌病的机会性真菌的体外活性。
Int J Antimicrob Agents. 2007 Aug;30(2):157-61. doi: 10.1016/j.ijantimicag.2007.04.004. Epub 2007 Jun 6.
9
Comparison of in vitro activities of antifungal drugs and ethanolic extract of propolis against Trichophyton rubrum and T. mentagrophytes by using a microdilution assay.采用微量稀释法比较抗真菌药物与蜂胶乙醇提取物对红色毛癣菌和须癣毛癣菌的体外活性。
Mycoses. 2005 May;48(3):205-10. doi: 10.1111/j.1439-0507.2005.01128.x.
10
A modified Christensen's urea and CLSI broth microdilution method for testing susceptibilities of six Malassezia species to voriconazole, itraconazole, and ketoconazole.一种改良的克里斯滕森尿素和CLSI肉汤微量稀释法，用于检测六种马拉色菌属菌种对伏立康唑、伊曲康唑和酮康唑的敏感性。
J Clin Microbiol. 2006 Sep;44(9):3429-31. doi: 10.1128/JCM.00989-06.
引用本文的文献
1
Antifungal Selection for the Treatment of Onychomycosis: Patient Considerations and Outcomes.治疗甲癣的抗真菌药物选择：患者考量与治疗结果
Infect Drug Resist. 2024 Mar 4;17:819-843. doi: 10.2147/IDR.S431526. eCollection 2024.
2
Dermatophytosis caused by Nannizzia nana (Microsporum nanum): a comprehensive review on a novel pathogen.由微小毛癣菌（毛癣菌属）引起的皮肤癣菌病：对一种新型病原体的全面综述。
Braz J Microbiol. 2023 Mar;54(1):509-521. doi: 10.1007/s42770-022-00880-5. Epub 2022 Nov 28.
3
Virulence and Antifungal Susceptibility of Strains from Animals and Humans.来自动物和人类的菌株的毒力及抗真菌药敏性
Antibiotics (Basel). 2021 Mar 12;10(3):296. doi: 10.3390/antibiotics10030296.
4
Antifungal Drug Susceptibility Testing of Dermatophytes: Laboratory Findings to Clinical Implications.皮肤癣菌的抗真菌药敏试验：从实验室结果到临床意义
Indian Dermatol Online J. 2019 May-Jun;10(3):225-233. doi: 10.4103/idoj.IDOJ_146_19.
5
Comparison of the in vitro activities of newer triazoles and established antifungal agents against Trichophyton rubrum.新型三唑类药物与已有的抗真菌药物对红色毛癣菌的体外活性比较。
Antimicrob Agents Chemother. 2015 Jul;59(7):4312-4. doi: 10.1128/AAC.00244-15. Epub 2015 Apr 20.
6
In-vitro Activity of 10 Antifungal Agents against 320 Dermatophyte Strains Using Microdilution Method in Tehran.在德黑兰采用微量稀释法检测10种抗真菌药物对320株皮肤癣菌的体外活性。
Iran J Pharm Res. 2013 Summer;12(3):537-45.
7
Standardization of hyphal growth inhibition rate as a means of evaluating Microsporum spp. in vitro susceptibility to terbinafine, griseofulvin, and ciclopiroxolamine.以菌丝生长抑制率为标准评估体外特比萘芬、灰黄霉素和环吡酮胺对须癣毛癣菌的敏感性。
Mycopathologia. 2011 Oct;172(4):279-85. doi: 10.1007/s11046-011-9433-7. Epub 2011 May 25.
8
Comparison of the activities of four antifungal agents in an in vitro model of dermatophyte nail infection.四种抗真菌药物在皮肤癣菌性甲感染体外模型中的活性比较。
Indian J Dermatol. 2008;53(3):125-8. doi: 10.4103/0019-5154.43216.
9
Identification of dermatophytes by an oligonucleotide array.利用寡核苷酸阵列鉴定皮肤癣菌
J Clin Microbiol. 2007 Oct;45(10):3160-6. doi: 10.1128/JCM.00829-07. Epub 2007 Aug 8.
10
In vivo efficacy and pharmacokinetics of voriconazole in an animal model of dermatophytosis.伏立康唑在皮肤癣菌病动物模型中的体内疗效及药代动力学
Antimicrob Agents Chemother. 2007 Sep;51(9):3317-21. doi: 10.1128/AAC.01185-06. Epub 2007 Jun 18.
本文引用的文献
1
Comparative study of susceptibilities of germinated and ungerminated conidia of Aspergillus fumigatus to various antifungal agents.烟曲霉萌发和未萌发分生孢子对多种抗真菌药物敏感性的比较研究。
J Clin Microbiol. 1999 Mar;37(3):858-61. doi: 10.1128/JCM.37.3.858-861.1999.
2
In vitro evaluation of voriconazole against clinical isolates of yeasts, moulds and dermatophytes in comparison with itraconazole, ketoconazole, amphotericin B and griseofulvin.伏立康唑与伊曲康唑、酮康唑、两性霉素B和灰黄霉素相比，对酵母、霉菌和皮肤癣菌临床分离株的体外评价
Mycoses. 1998 Sep-Oct;41(7-8):309-19. doi: 10.1111/j.1439-0507.1998.tb00344.x.
3
An overview of topical antifungal therapy in dermatomycoses. A North American perspective.皮肤真菌病的局部抗真菌治疗概述。北美视角。
Drugs. 1998 May;55(5):645-74. doi: 10.2165/00003495-199855050-00004.
4
In vitro activity of the new triazole voriconazole (UK-109,496) against opportunistic filamentous and dimorphic fungi and common and emerging yeast pathogens.新型三唑类药物伏立康唑（UK-109,496）对机会性丝状真菌和双相真菌以及常见和新出现的酵母病原体的体外活性。
J Clin Microbiol. 1998 Jan;36(1):198-202. doi: 10.1128/JCM.36.1.198-202.1998.
5
Comparison of in vitro antifungal susceptibilities of conidia and hyphae of filamentous fungi.丝状真菌分生孢子与菌丝体外抗真菌药敏性比较
Antimicrob Agents Chemother. 1997 Dec;41(12):2760-2. doi: 10.1128/AAC.41.12.2760.
6
In vitro evaluation of voriconazole against some clinically important fungi.伏立康唑对某些临床重要真菌的体外评价。
Antimicrob Agents Chemother. 1997 Aug;41(8):1832-4. doi: 10.1128/AAC.41.8.1832.
7
Oral terbinafine (Lamisil) in the treatment of fungal infections of the skin and nails.口服特比萘芬（兰美抒）治疗皮肤和指甲真菌感染。
Dermatology. 1997;194 Suppl 1:37-9. doi: 10.1159/000246183.
8
In vitro studies of activity of voriconazole (UK-109,496), a new triazole antifungal agent, against emerging and less-common mold pathogens.新型三唑类抗真菌药物伏立康唑（UK-109,496）对新出现的及较少见霉菌病原体活性的体外研究。
Antimicrob Agents Chemother. 1997 Apr;41(4):841-3. doi: 10.1128/AAC.41.4.841.
9
Effects of incubation temperature, inoculum size, and time of reading on broth microdilution susceptibility test results for amphotericin B fgainst Fusarium.孵育温度、接种量及读数时间对两性霉素B抗镰刀菌肉汤微量稀释药敏试验结果的影响
Antimicrob Agents Chemother. 1997 Apr;41(4):808-11. doi: 10.1128/AAC.41.4.808.
10
Comparison study of broth macrodilution and microdilution antifungal susceptibility tests for the filamentous fungi.丝状真菌肉汤宏稀释法和微稀释法抗真菌药敏试验的比较研究
Antimicrob Agents Chemother. 1996 Sep;40(9):2106-10. doi: 10.1128/AAC.40.9.2106.
Zotero 插件