一种阻燃聚氨酯泡沫燃烧产物的极高毒性。

Extreme toxicity from combustion products of a fire-retarded polyurethane foam.

作者信息

Petajan J H, Voorhees K J, Packham S C, Baldwin R C, Einhorn I N, Grunnet M L, Dinger B G, Birky M M

出版信息

Science. 1975 Feb 28;187(4178):742-4. doi: 10.1126/science.1114319.

Abstract

The products from nonflaming combustion of wood and a trimethylol-propane-based rigid-urethane foam that was not fire-retarded produced elevated carboxyhemoglobin levels but no abnormal neurological effects. However, when this type of foam contained a reactive phosphate fire retardant, the combustion products caused grand mal seizures and death in rats. The toxic combustion product responsible for the seizures has been identified as 4-ethyl-1-phospha-2,6,7-trioxabicyclo(2.2.2.)octane-1-oxide.

摘要

木材与未添加阻燃剂的基于三羟甲基丙烷的硬质聚氨酯泡沫进行无焰燃烧所产生的产物，会使碳氧血红蛋白水平升高，但未产生异常神经效应。然而，当这类泡沫含有反应性磷酸盐阻燃剂时，其燃烧产物会导致大鼠发生癫痫大发作并死亡。已确定导致癫痫发作的有毒燃烧产物为4-乙基-1-磷杂-2,6,7-三氧杂双环(2.2.2)辛烷-1-氧化物。