Mullen D J, Eisen R N, Newman R D, Perrone P M, Wilsey J C
Department of Radiology, Greenwich Hospital, 5 Perryridge Rd, Greenwich, CT 06830, USA.
Radiology. 2001 Jan;218(1):255-60. doi: 10.1148/radiology.218.1.r01ja33255.
To investigate the use of activated charcoal to mark the biopsy site and needle track after large-core-needle breast biopsy.
Three hundred seventy-six consecutive patients (with 383 lesions) were referred for stereotactic breast biopsy. Two hundred forty-seven lesions were carbon marked when the need for surgery was likely. Patients who underwent marking were followed up for the results of surgery or mammography performed at our institution. Specimen sizes obtained by using the carbon mark were compared with sizes of consecutive biopsy specimens obtained after hook-wire localization.
Carbon marking was well tolerated in all cases. All 132 surgeries performed at the authors' institution were successful in removing the marked target. Specimen sizes compared favorably with sizes of comparison hook-wire localization specimens. All 68 lesions followed mammographically revealed no changes that were attributable to the use of carbon. Two minor complications were observed. Two small cancers were completely removed at needle biopsy.
Carbon marking is safe and effective for marking the biopsy site and needle track created by stereotactic large-core-needle biopsy of the breast. Marking eliminates the need for postprocedural needle localization. It remains effective when small lesions have been completely removed. This technique should be considered in properly selected cases by those performing large-core-needle biopsy of the breast.
探讨在粗针乳腺活检后使用活性炭标记活检部位和针道的情况。
376例连续患者（共383个病灶）接受了立体定向乳腺活检。当可能需要手术时，对247个病灶进行了碳标记。对接受标记的患者进行随访，以了解在本机构进行的手术或乳腺X线摄影结果。将使用碳标记获取的标本大小与在钩丝定位后连续获取的活检标本大小进行比较。
所有病例对碳标记的耐受性良好。作者所在机构进行的132例手术均成功切除了标记的目标病灶。标本大小与对照钩丝定位标本的大小相比具有优势。乳腺X线摄影随访的所有68个病灶均未发现因使用碳而导致的变化。观察到2例轻微并发症。2例小癌在针吸活检时被完全切除。
碳标记对于立体定向粗针乳腺活检所造成的活检部位和针道标记是安全有效的。标记消除了术后针定位的必要性。当小病灶被完全切除时，它仍然有效。进行乳腺粗针活检的人员在适当选择的病例中应考虑采用该技术。
