Verbraak F D, Schreinemachers M C, Tiller A, van Deventer S J, de Smet M D
Department of Ophthalmology, Academic Medical Center, University of Amsterdam, P O Box 22700, 1100 DE Amsterdam, The Netherlands.
Br J Ophthalmol. 2001 Feb;85(2):219-21. doi: 10.1136/bjo.85.2.219.
To assess the prevalence of subclinical anterior uveitis in adult patients with inflammatory bowel disease.
In 179 consecutive patients (96 with Crohn's disease, 55 with ulcerative colitis, and 28 with inflammatory bowel disease of undetermined nature) without previous or concurrent ocular complaints, quantitative flare measurements were obtained with the Kowa FC laser flare to detect the presence of subclinical uveitis.
The mean flare value was 3.9 (SD 1.1) ph/ms in patients younger than 30 years of age, rising to 5.8 (2.5) ph/ms in those over 60 years of age. No measurement performed in this patient population fell outside the mean observed value plus or minus SD of the normal controls within the same age category.
In an adult population of 179 consecutive patients with inflammatory bowel disease the presence of a form of subclinical uveitis, as described by Hofley et al in a group of juvenile patients, is highly unlikely.
评估成年炎症性肠病患者中亚临床前葡萄膜炎的患病率。
对179例既往无眼部疾病且无眼部相关症状的连续性患者(96例克罗恩病患者、55例溃疡性结肠炎患者、28例未定型炎症性肠病患者),采用Kowa FC激光散射仪进行定量散射测量,以检测亚临床葡萄膜炎的存在。
年龄小于30岁患者的平均散射值为3.9(标准差1.1)ph/ms,60岁以上患者的平均散射值升至5.8(2.5)ph/ms。该患者群体的测量值均未超出同一年龄组正常对照组平均观察值加减标准差的范围。
在179例连续性成年炎症性肠病患者中,如Hofley等人在一组青少年患者中所描述的那种亚临床葡萄膜炎形式极不可能存在。