可生物降解的聚合物纳米颗粒作为药物递送载体。

Biodegradable polymeric nanoparticles as drug delivery devices.

作者信息

Soppimath K S, Aminabhavi T M, Kulkarni A R, Rudzinski W E

机构信息

Department of Chemistry, Polymer Research Group, Karnatak University, Dharwad 580 003, India.

出版信息

J Control Release. 2001 Jan 29;70(1-2):1-20. doi: 10.1016/s0168-3659(00)00339-4.

DOI:10.1016/s0168-3659(00)00339-4

PMID:11166403

Abstract

This review presents the most outstanding contributions in the field of biodegradable polymeric nanoparticles used as drug delivery systems. Methods of preparation, drug loading and drug release are covered. The most important findings on surface modification methods as well as surface characterization are covered from 1990 through mid-2000.

摘要

本综述介绍了用作药物递送系统的可生物降解聚合物纳米颗粒领域最杰出的贡献。涵盖了制备方法、药物负载和药物释放。涵盖了1990年至2000年年中关于表面改性方法以及表面表征的最重要发现。