Cioffi G A, Mansberger S, Spry P, Johnson C, Van Buskirk E M
Devers Eye Institute, Portland, Oregon, USA.
Trans Am Ophthalmol Soc. 2000;98:195-9; discussion 199-202.
Frequency Doubling Technology (FDT) perimetry is a novel perimetric test that provides rapid screening (45 to 60 seconds) and full-threshold (4 to 5 minutes) testing for detection of vision loss. The purpose of this study was to determine the specificity and sensitivity of FDT perimetry for the detection of ocular disease.
A total of 130 participants (257 eyes of 42 men and 88 women) recruited from the community completed FDT perimetry, standard achromatic automated perimetry (SAP), anterior segment biomicroscopy, tonometry, and dilated ophthalmoscopy. FDT results were considered abnormal if 1 point was abnormal (depressed below the 5% level on the screening protocol C-20-5). SAP was considered abnormal if the glaucoma hemifield test or pattern standard deviation was outside normal limits (P < .05) or a hemifield cluster of 3 depressed points on the pattern deviation probability plot (P < .05) was present. An abnormal eye examination was defined as the presence of an abnormality in the anterior segment, lens, or posterior segment that was likely to cause a visual field defect or the presence of glaucomatous or other optic neuropathy.
The mean age (+/- SD) of participants was 55.5 years (+/- 10.3). Ethnic groups, as reported by participants, included 77 (59%) African Americans, 40 (31%) Caucasians, and 13 (10%) in other groups. On clinical examination, 116 eyes (45%) were normal, 9 eyes (3.5%) had a cataract with best corrected visual acuity worse than 20/30, 16 eyes (6%) had open-angle glaucoma, and 17 eyes (7%) had retinal findings or lesions that were likely to cause a visual field defect. For FDT perimetry, 22 (8.6%) of 257 tests were unreliable, and for SAP, 65 (25.3%) of 257 tests were unreliable. The sensitivity and specificity of FDT perimetry for detecting an abnormal clinical examination were 55% and 90% and for detecting an abnormal examination that included an abnormal SAP, 64% and 86%.
FDP demonstrated reasonable discriminatory power for detecting eye disease.
倍频技术（FDT）视野检查是一种新型视野检查方法，可提供快速筛查（45至60秒）和全阈值（4至5分钟）检查以检测视力丧失。本研究的目的是确定FDT视野检查检测眼部疾病的特异性和敏感性。
从社区招募的130名参与者（42名男性和88名女性的257只眼睛）完成了FDT视野检查、标准消色差自动视野检查（SAP）、眼前节生物显微镜检查、眼压测量和散瞳眼底检查。如果1个点异常（在筛查方案C-20-5中低于5%水平），则FDT结果被视为异常。如果青光眼半视野检查或模式标准差超出正常范围（P <.05）或模式偏差概率图上有3个压低点的半视野簇（P <.05），则SAP被视为异常。异常眼部检查定义为眼前节、晶状体或后节存在可能导致视野缺损的异常，或存在青光眼或其他视神经病变。
参与者的平均年龄（±标准差）为55.5岁（±10.3）。参与者报告的种族群体包括77名（59%）非裔美国人、40名（31%）白种人和13名（10%）其他群体。临床检查中，116只眼睛（45%）正常，9只眼睛（3.5%）患有白内障且最佳矫正视力低于20/30，16只眼睛（6%）患有开角型青光眼，17只眼睛（7%）有视网膜病变或病变可能导致视野缺损。对于FDT视野检查，257次检查中有22次（8.6%）不可靠，对于SAP，257次检查中有65次（25.3%）不可靠。FDT视野检查检测异常临床检查的敏感性和特异性分别为55%和90%，检测包括异常SAP的异常检查的敏感性和特异性分别为64%和86%。
FDP在检测眼部疾病方面显示出合理的鉴别能力。
