Cello K E, Nelson-Quigg J M, Johnson C A
Department of Ophthalmology, University of California, Davis, California, USA.
Am J Ophthalmol. 2000 Mar;129(3):314-22. doi: 10.1016/s0002-9394(99)00414-6.
To evaluate the ability of frequency doubling technology perimetry to detect early, moderate, and advanced glaucomatous visual field loss.
In a prospective study, frequency doubling technology perimetry (C-20 full threshold) was performed in the right eye of 254 normal control subjects and 230 patients with early (n = 85), moderate (n = 114), or advanced (n = 31) glaucomatous visual field loss. Previous Humphrey Field Analyzer test results were used to classify glaucomatous visual field loss as early (mean deviation no worse than -6 dB), moderate (mean deviation between -6 and -12 dB) or advanced (mean deviation between -12 and -22 dB).
Receiver operating characteristic curves showed 100% sensitivity and specificity (area under the curve, 1.0) for detecting advanced glaucomatous visual field loss, approximately 96% sensitivity and 96% specificity (area under the curve, 0.9751) for detecting moderate glaucomatous visual field loss, and approximately 85% sensitivity and 90% specificity (area under the curve, 0.9261) for early glaucomatous visual field loss.
Frequency doubling technology perimetry demonstrates high sensitivity and specificity for detection of early, moderate, and advanced glaucomatous visual field loss.
评估倍频技术视野检查检测早期、中度和晚期青光眼性视野缺损的能力。
在一项前瞻性研究中，对254名正常对照者及230例患有早期（n = 85）、中度（n = 114）或晚期（n = 31）青光眼性视野缺损的患者的右眼进行倍频技术视野检查（C - 20全阈值）。以前的Humphrey视野分析仪测试结果用于将青光眼性视野缺损分类为早期（平均偏差不超过 - 6 dB）、中度（平均偏差在 - 6至 - 12 dB之间）或晚期（平均偏差在 - 12至 - 22 dB之间）。
受试者工作特征曲线显示，检测晚期青光眼性视野缺损的灵敏度和特异度均为100%（曲线下面积为1.0），检测中度青光眼性视野缺损的灵敏度约为96%，特异度约为96%（曲线下面积为0.9751），检测早期青光眼性视野缺损的灵敏度约为85%，特异度约为90%（曲线下面积为0.9261）。
倍频技术视野检查在检测早期、中度和晚期青光眼性视野缺损方面显示出高灵敏度和特异度。
