Baldwin R P
Department of Chemistry, University of Louisville, KY 40292, USA.
Electrophoresis. 2000 Dec;21(18):4017-28. doi: 10.1002/1522-2683(200012)21:18<4017::AID-ELPS4017>3.0.CO;2-5.
Recent advances in the design and application of electrochemical (EC) detection systems in capillary electrophoresis (CE) are reviewed, with the objective of providing the nonelectrochemist with a state-of-the-art picture of CEEC instrumentation and an overview of the principal analytes for which CEEC is best suited. The detection schemes considered here include those based both on amperometry and on potentiometry as both kinds of EC systems are being actively developed in CE and have the potential for broad application in analysis. Over the three-year period covered by this review, an important direction that CEEC has taken is the construction of more complex electrode systems beginning with the use of multiple EC electrodes and culminating with the adaptation of EC detection to microfabricated "lab-on-a-chip" analysis devices. In addition, CEEC applications have now grown to include a broad variety of inorganic, organic, and biochemical analytes and samples.
本文综述了毛细管电泳（CE）中电化学（EC）检测系统在设计和应用方面的最新进展，旨在为非电化学领域的人员提供CEEC仪器的最新情况，并概述CEEC最适合检测的主要分析物。这里讨论的检测方案包括基于安培法和电位法的方案，因为这两种EC系统在CE中都在积极研发，并且在分析中具有广泛应用的潜力。在本综述涵盖的三年期间，CEEC的一个重要发展方向是构建更复杂的电极系统，从使用多个EC电极开始，最终发展到将EC检测应用于微制造的“芯片实验室”分析设备。此外，CEEC的应用现已扩展到包括各种各样的无机、有机和生化分析物及样品。
