Noda M, Matsuda S, Kobayashi M
Division of 2nd. Microbiology, Hiroshima Prefectural Institute for Public Health and Environment Science.
Kansenshogaku Zasshi. 2000 Dec;74(12):1023-31. doi: 10.11150/kansenshogakuzasshi1970.74.1023.
First, four disinfectants were tested for virucidal activity on viruses coated upon materials. Disinfectants of the aldehyde and halogen groups had a destructive effect on both enveloped and non-enveloped DNA and RNA viruses coated on a cotton gauze, stainless chips, wood shavings, polyplopylene resin chips and latex resin chips, respectively. Disinfectant of the biguanide group had a virucidal activity on both enveloped DNA and RNA viruses. Secondary, five disinfectants were tested for the durability of their virucidal activity on two DNA and RNA viruses after preparing working solutions. The disinfectants of the aldehyde group maintained their virucidal efficiency for 2 to 3 days. Disinfectants of the invert and amphoteric soap groups, the biguanide group and the halogen group maintained their virucidal efficiency for 1 to 2 days. In the presence of bovine serum, the virucidal activity of the aldehyde group and the halogen group were not influenced but that of the invert and amphoteric soap groups were strongly influenced and lost their effect.
首先,测试了四种消毒剂对涂覆在材料上的病毒的杀病毒活性。醛类和卤素类消毒剂分别对涂覆在棉纱、不锈钢芯片、木刨花、聚丙烯树脂芯片和乳胶树脂芯片上的包膜和非包膜DNA及RNA病毒具有破坏作用。双胍类消毒剂对包膜DNA和RNA病毒均具有杀病毒活性。其次,在制备工作溶液后,测试了五种消毒剂对两种DNA和RNA病毒的杀病毒活性的耐久性。醛类消毒剂的杀病毒效率可维持2至3天。酯类和两性皂类、双胍类和卤素类消毒剂的杀病毒效率可维持1至2天。在牛血清存在的情况下,醛类和卤素类消毒剂的杀病毒活性不受影响,但酯类和两性皂类消毒剂的杀病毒活性受到强烈影响并失去作用。