Masuda S, Terada A, Fujisawa T, Iguchi K
Department of Otorhinolaryngology, National Mie Hospital.
Arerugi. 2000 Dec;49(12):1138-45.
Recently, the number of patients with Japanese cedar (Cryptomeria japonica) pollinosis has increased, especially in children. However, little is known about the incidence in infants. We studied on the rate of sensitization and the onset of pollinosis in children under 6 years old. The percentage of positive CAP-RAST to Japanese cedar pollen was 27.6%, in 76 infants (51 male and 25 female, 2 months-5 years old) who visited National Mie Hospital pediatric allergy clinic due to bronchial asthma and/or atopic dermatitis. The youngest child who has been sensitized to pollen was 1 year 8 month old boy. The percentage of positive rate of CAP-RAST to house dust mite was 61.8%. Twenty-seven infants (20 male and 7 female, 2-5 years of age) were diagnosed as Japanese cedar pollinosis in National Mie Hospital Otorhinolaryngology clinic in 1999 and 2000. The youngest child with pollinosis was 2 year 5 month old boy. Most of the 27 infants complained of rhinorrhea and/or eye symptoms and some of them complained cough, snoring, or epistaxis. About 40% were sensitized to Japanese cedar and/or cupressaceae pollen alone, 60% were also sensitized to house dust mite. In conclusion, it is possible that the sensitization to Japanese cedar pollen occurs after 2 season of pollen exposure and pollinosis occurs in 2 years old. Japanese cedar pollen has been an important allergen not only in school children, but also in infants.
近年来，日本柳杉花粉症患者数量有所增加，尤其是儿童患者。然而，关于婴儿的发病率却知之甚少。我们对6岁以下儿童的致敏率和花粉症发病情况进行了研究。在因支气管哮喘和/或特应性皮炎前往三重县立医院儿科过敏门诊就诊的76名婴儿（男51名，女25名，年龄2个月至5岁）中，日本柳杉花粉CAP-RAST阳性率为27.6%。最早对花粉致敏的儿童是一名1岁8个月大的男孩。屋尘螨CAP-RAST阳性率为61.8%。1999年和2000年，三重县立医院耳鼻咽喉科门诊诊断出27名婴儿（男20名，女7名，年龄2至5岁）患有日本柳杉花粉症。最早患花粉症的儿童是一名2岁5个月大的男孩。这27名婴儿中大多数有流涕和/或眼部症状，部分婴儿有咳嗽、打鼾或鼻出血症状。约40%仅对日本柳杉和/或柏科花粉致敏，60%还对屋尘螨致敏。总之，接触花粉两个季节后可能会对日本柳杉花粉致敏，2岁时可能会发生花粉症。日本柳杉花粉不仅是学童，也是婴儿的重要过敏原。
