Renz J F, Busuttil R W
Department of Surgery, University of California San Francisco, California, USA.
Semin Liver Dis. 2000;20(4):411-24. doi: 10.1055/s-2000-13153.
Adult-to-adult living-donor liver transplantation is the most recent achievement in the evolution of strategies to increase donor organ supply. Justification of the procedure has evolved from increased organ-waiting times, wait-list morbidity and mortality of adult transplant candidates. Successful application of adult-to-adult living-donor liver transplantation mandates unique surgical, medical, and donor considerations as these procedures predispose to unique complications resulting from anatomic variations, technical considerations, and the transplantation of "partial" grafts. Additionally, because the magnitude of the donor operation is greater and potentially fraught with serious short and long term morbidity and possibly mortality, the utilization of living-donors for adult liver transplantation raises bio-ethical concerns heretofore not encountered. This review explores the current state of adult-to-adult living-donor liver transplantation.
成人对成人活体肝移植是增加供体器官供应策略发展中的最新成果。该手术的合理性已从成人移植受者器官等待时间的增加、等待名单上的发病率和死亡率演变而来。成人对成人活体肝移植的成功应用需要独特的外科、医学和供体方面的考虑，因为这些手术容易因解剖变异、技术因素以及“部分”移植物的移植而引发独特的并发症。此外，由于供体手术的规模更大，并且可能充满严重的短期和长期发病率甚至可能有死亡率，利用活体供体进行成人肝移植引发了前所未有的生物伦理问题。本综述探讨了成人对成人活体肝移植的现状。
