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三维打印:医学及肝脏手术应用综述

Three-dimensional printing: review of application in medicine and hepatic surgery.

作者信息

Yao Rui, Xu Gang, Mao Shuang-Shuang, Yang Hua-Yu, Sang Xin-Ting, Sun Wei, Mao Yi-Lei

机构信息

Biomanufacturing Center, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China.

Department of Liver Surgery, Peking Union Medical College (PUMC) Hospital, PUMC and Chinese Academy of Medical Sciences, Beijing 100730, China.

出版信息

Cancer Biol Med. 2016 Dec;13(4):443-451. doi: 10.20892/j.issn.2095-3941.2016.0075.

DOI:10.20892/j.issn.2095-3941.2016.0075
PMID:28154775
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5250601/
Abstract

Three-dimensional (3D) printing (3DP) is a rapid prototyping technology that has gained increasing recognition in many different fields. Inherent accuracy and low-cost property enable applicability of 3DP in many areas, such as manufacturing, aerospace, medical, and industrial design. Recently, 3DP has gained considerable attention in the medical field. The image data can be quickly turned into physical objects by using 3DP technology. These objects are being used across a variety of surgical specialties. The shortage of cadaver specimens is a major problem in medical education. However, this concern has been solved with the emergence of 3DP model. Custom-made items can be produced by using 3DP technology. This innovation allows 3DP use in preoperative planning and surgical training. Learning is difficult among medical students because of the complex anatomical structures of the liver. Thus, 3D visualization is a useful tool in anatomy teaching and hepatic surgical training. However, conventional models do not capture haptic qualities. 3DP can produce highly accurate and complex physical models. Many types of human or animal differentiated cells can be printed successfully with the development of 3D bio-printing technology. This progress represents a valuable breakthrough that exhibits many potential uses, such as research on drug metabolism or liver disease mechanism. This technology can also be used to solve shortage of organs for transplant in the future.

摘要

三维(3D)打印(3DP)是一种快速成型技术,在许多不同领域中得到了越来越多的认可。固有的精度和低成本特性使得3DP在许多领域具有适用性,如制造业、航空航天、医疗和工业设计。最近,3DP在医学领域受到了相当大的关注。通过使用3DP技术,图像数据可以快速转化为实物。这些实物正在被应用于各种外科专业。尸体标本的短缺是医学教育中的一个主要问题。然而,随着3DP模型的出现,这个问题得到了解决。使用3DP技术可以生产定制物品。这一创新使得3DP可用于术前规划和手术训练。由于肝脏解剖结构复杂,医学生学习起来很困难。因此,三维可视化是解剖学教学和肝脏外科手术训练中的一个有用工具。然而,传统模型无法捕捉触觉特性。3DP可以生产高度精确和复杂的实物模型。随着3D生物打印技术的发展,许多类型的人类或动物分化细胞都可以成功打印。这一进展代表了一个有价值的突破,具有许多潜在用途,如药物代谢或肝脏疾病机制的研究。这项技术未来还可用于解决器官移植短缺问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b278/5250601/af0cf64de4f5/cbm-13-4-443-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b278/5250601/af0cf64de4f5/cbm-13-4-443-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b278/5250601/af0cf64de4f5/cbm-13-4-443-1.jpg

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