Stewart A, Porter R W, Primrose W R, Walker L G, Reid D M
Department of Medicine and Therapeutics, University of Aberdeen, UK.
Clin Rheumatol. 1999;18(3):201-6. doi: 10.1007/s100670050085.
We examined 310 hip fracture patients (55 men, 255 women) to identify differences in those patients who had suffered a cervical fracture compared with those with a trochanteric fracture of the hip. Patients underwent a dual-energy X-ray absorptiometry (DXA) scan of their hip and total body and quantitative ultrasound (QUS) scans of their heel. Other measurements included medical/drug history. Significant differences were found for broadband ultrasound attenuation (BUA) and DXA total-body measurements, with those with a cervical fracture having a higher bone mass. Those with a trochanteric fracture showed a significantly higher incidence of stroke (12.8% vs. 6.3%, p = 0.05), while high blood pressure/antihypertensive therapy was significantly more common in the cervical fracture group (11.6% vs. 4.3%, p < 0.03). Therefore, it is not only bone parameters that differ in these patients. In the presence of certain medical conditions, preventative therapy may be directed to managing co-existing conditions as well as improving bone density.
我们对310例髋部骨折患者(55例男性,255例女性)进行了检查,以确定髋部发生颈椎骨折的患者与髋部转子间骨折患者之间的差异。患者接受了髋部和全身的双能X线吸收测定法(DXA)扫描以及足跟的定量超声(QUS)扫描。其他测量包括病史/用药史。发现宽带超声衰减(BUA)和DXA全身测量存在显著差异,颈椎骨折患者的骨量较高。转子间骨折患者的中风发生率显著更高(12.8%对6.3%,p = 0.05),而高血压/抗高血压治疗在颈椎骨折组中显著更为常见(11.6%对4.3%,p < 0.03)。因此,这些患者不仅在骨参数方面存在差异。在存在某些医疗状况的情况下,预防性治疗可能既要针对管理并存疾病,也要针对改善骨密度。