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痤疮瘢痕——发病机制、评估及治疗选择

Acne Scarring-Pathogenesis, Evaluation, and Treatment Options.

作者信息

Connolly Deirdre, Vu Ha Linh, Mariwalla Kavita, Saedi Nazanin

机构信息

Drs. Connolly, Vu, and Saedi are with the Department of Dermatology and Cutaneous Biology at Thomas Jefferson University Hospital in Philadelphia, Pennsylvania.

Dr. Mariwalla is with Mariwalla Dermatology in West Islip, New York.

出版信息

J Clin Aesthet Dermatol. 2017 Sep;10(9):12-23. Epub 2017 Sep 1.

Abstract

Acne vulgaris is a ubiquitous problem affecting 80 percent of people ages 11 to 30 years, with many patients experiencing some degree of scarring. This review focuses on atrophic scars, the most common type of acne scar. We briefly address the cellular sequelae that lead to scar formation and the initial evaluation of patients with acne scars. We then discuss an algorithmic approach to the treatment of acne scarring based on the classification of scars into erythematous and atrophic types. Lastly, we discuss the future treatment of acne scars and ongoing clinical trials.

摘要

寻常痤疮是一个普遍存在的问题,影响着80%年龄在11至30岁的人群,许多患者会出现一定程度的瘢痕形成。本综述聚焦于萎缩性瘢痕,这是痤疮瘢痕最常见的类型。我们简要阐述导致瘢痕形成的细胞后遗症以及痤疮瘢痕患者的初步评估。然后,我们基于将瘢痕分为红斑型和萎缩型的分类方法,讨论一种治疗痤疮瘢痕的算法式方法。最后,我们探讨痤疮瘢痕的未来治疗以及正在进行的临床试验。

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