Chathra Namitha, Mysore Venkataram
Venkat Charmalaya-Centre for Advanced Dermatology and Postgraduate Training, 3437, 1st G Cross, 7 main, Subbanna Garden, Vijay Nagar, Bangalore, India.
J Cutan Aesthet Surg. 2018 Jan-Mar;11(1):20-25. doi: 10.4103/JCAS.JCAS_4_18.
The Er:YAG laser, considered to be less effective than CO laser in its traditional form, in its new modulated version has variable pulse technology that is claimed to be superior to the earlier versions of the laser.
The aim of the study was to check efficacy and safety of the new variable square pulse (VSP) Er:YAG laser in the management of acne scar in patients with Fitzpatrick skin types IV and V.
This retrospective study consisted of 80 patients (Fitzpatrick skin types IV and V) with atrophic and hypertrophic facial acne scars. Records of the patients who had undergone four treatment sessions with VSP technology equipped with Er:YAG laser were extracted. Each patient had undergone a minimum of four sessions. Fractional mode at medium laser pulse (SP) and long pulse (LP) was employed for the depressed center of the scars to stimulate neocollagenogenesis. Short laser pulse (MSP) in nonfractionated mode was used for ablating the raised scar border and hypertrophic scars. Goodman and Baron global scarring grading system was used for qualitative and quantitative assessments. Patient's satisfaction to the treatment and observer's assessment of improvement (based on photographs) was graded as poor (<25% improvement), fair (25-50% improvement), good (51-75% improvement), and excellent (>75% improvement).
At the end of the four sessions, the number of patients in grade IV postacne scarring reduced from 16 to 2 and that in grade III from 47 to 29. The mean score significantly dropped from 36.94 to 27.5. Subjective assessment revealed that 78 of 80 patients had noticed more than 25% improvement, with 50 of them showing more than 50% improvement at the end of four sessions. Eight patients perceived an excellent response and 42 reported a good response. This is notably higher than the observer's grading, which showed an excellent response in only 2 patients and a good response in 35. Adverse effects were limited to prolonged erythema (two patients), prolonged crusting (one patient), and postinflammatory hyperpigmentation (one patient).
Ninety-seven percent of the subjects in our study perceived at least a fair improvement. We also saw a significant change in the objective score with a fall of the mean quantitative score from 36.94 to 27.15. This underscores the new variable-pulsed Er:YAG laser's effectiveness in the treatment of acne scars. It also has the added advantage of lesser adverse events and faster healing.
传统形式的铒钇铝石榴石(Er:YAG)激光被认为比二氧化碳(CO)激光效果差,其新的调制版本具有可变脉冲技术,据称优于早期版本的激光。
本研究的目的是检验新型可变方波脉冲(VSP)Er:YAG激光治疗 Fitzpatrick IV型和V型皮肤患者痤疮瘢痕的疗效和安全性。
这项回顾性研究纳入了80例患有萎缩性和肥厚性面部痤疮瘢痕的患者(Fitzpatrick IV型和V型皮肤)。提取接受配备Er:YAG激光的VSP技术进行四次治疗的患者记录。每位患者至少接受了四次治疗。对于瘢痕凹陷中心采用中等激光脉冲(SP)和长脉冲(LP)的分次模式来刺激新胶原形成。非分次模式下的短激光脉冲(MSP)用于烧灼隆起的瘢痕边缘和肥厚性瘢痕。采用古德曼和巴伦整体瘢痕分级系统进行定性和定量评估。患者对治疗的满意度以及观察者基于照片对改善情况的评估分为差(改善<25%)、一般(改善25 - 50%)、好(改善51 - 75%)和优(改善>75%)。
在四次治疗结束时,IV级痤疮后瘢痕患者数量从16例减少至2例,III级从( )47例减少至29例。平均评分从36.94显著降至27.5。主观评估显示,80例患者中有78例注意到改善超过25%,其中50例在四次治疗结束时改善超过50%。8例患者认为反应极佳,42例报告反应良好。这明显高于观察者的分级,观察者分级显示仅2例反应极佳,35例反应良好。不良反应仅限于红斑持续时间延长(2例患者)、结痂持续时间延长(1例患者)和炎症后色素沉着(1例患者)。
我们研究中97%的受试者至少有一般程度的改善。我们还看到客观评分有显著变化,平均定量评分从36.94降至27.15。这突出了新型可变脉冲Er:YAG激光治疗痤疮瘢痕的有效性。它还具有不良事件较少和愈合较快的额外优势。