van Hest N A, Smit F, Verhave J P
Gemeentelijke Gezondheidsdienst voor Rotterdam en omstreken, afd. Tuberculosebestrijding, Postbus 70.032, 3000 LP Rotterdam.
Ned Tijdschr Geneeskd. 2001 Jan 27;145(4):175-9.
To estimate the completeness of notification of malaria by physicians and laboratories in the Netherlands.
Capture-recapture analysis was applied to three incomplete, partially overlapping registers of malaria cases in 1995 and 1996: a laboratory survey, the Notification Office and the hospital admission registration.
The average response of the 107 laboratories approached was 83.6% over both years. In 1995 and 1996 581 and 535 malaria cases respectively were microscopically diagnosed. In each year physicians officially notified 311 patients. 350 and 330 patients respectively were admitted to hospital. Capture-recapture analysis estimated the total number of new malaria cases at 933 (95% confidence interval: 849-1072) in 1995 and at 774 cases (740-821) in 1996. The estimated completeness of notification in 1995 and 1996 was therefore 33.3% and 40.2% for physicians and 62.3% and 69.1% for the laboratories.
Laboratory-based notification, introduced in the Infectious Diseases Act, can considerably increase the number of officially reported malaria cases as compared with notification by physicians. However, approximately one-third of the estimated number of cases may still go unreported.
评估荷兰医生和实验室对疟疾通报的完整性。
采用捕获-再捕获分析法，对1995年和1996年三个不完整且部分重叠的疟疾病例登记册进行分析，这三个登记册分别为实验室调查、通报办公室及医院入院登记。
在这两年中，所调查的107家实验室的平均回应率为83.6%。1995年和1996年分别通过显微镜诊断出581例和535例疟疾病例。每年医生正式通报的患者有311例。分别有350例和330例患者入院治疗。捕获-再捕获分析估计1995年新疟疾病例总数为933例（95%置信区间：849 - 1072），1996年为774例（740 - 821）。因此，1995年和1996年医生通报的估计完整性分别为33.3%和40.2%，实验室的通报完整性分别为62.3%和69.1%。
《传染病法》引入的基于实验室的通报与医生通报相比，可大幅增加官方报告的疟疾病例数量。然而，估计病例数中仍约有三分之一可能未被报告。
