Akaĭzin E S
State Medical Academy, Ivanovo, Russia.
Zh Mikrobiol Epidemiol Immunobiol. 2000 Sep-Oct(5):82-4.
The influence of oleic acid on the process of the destruction of E. coli, induced by the transfer of the bacteria from the growth medium into solution without nutrient substances and their treatment with oleic acid at a temperature of 45 degrees C, was studied. Oleic acid at a concentration of 200 nmol/ml accelerated the destruction of E. coli in comparison with the control organisms, but did not lead to the significant increase of the final degree of the destruction of biomass. The dynamics of the inclusion of labeled oleic acid into E. coli cell fractions after the induction of autolysis was analyzed. The radioactive label was most actively included into the lipid (chloroform) fraction of bacterial biopolymers. Simultaneously with the destruction of some cells in the population the inclusion of labeled oleic acid into intact cells was found to occur.
研究了油酸对大肠杆菌破坏过程的影响。该破坏过程是通过将细菌从生长培养基转移到无营养物质的溶液中，并在45摄氏度下用油酸处理来诱导的。与对照生物相比，浓度为200 nmol/ml的油酸加速了大肠杆菌的破坏，但并未导致生物量最终破坏程度的显著增加。分析了自溶诱导后标记油酸掺入大肠杆菌细胞组分的动力学。放射性标记最活跃地掺入细菌生物聚合物的脂质（氯仿）组分中。在群体中一些细胞被破坏的同时，发现标记油酸也会掺入完整细胞中。
