Su K L, Schmid H H
Biochim Biophys Acta. 1975 Jan 24;380(1):119-26. doi: 10.1016/0005-2760(75)90050-8.
[U-14-C]Phytol (3,7,11,15-tetramethylhexadec-2-en-1-ol) and [U-14-C]dihydrophytol (3,7,11,15-tetramethylhexadecanol) were administered intracerebrally to 18-day-old rats and incorporation of radioactivity into brain lipids was determined after 6 and 24 h. Radioactivity from [U-14-C]phytol was found in free phytenic (3,7,11,15-tetramethylhexadec-2-enoic), phytanic (3,7,11,15-tetramethylhexadecanoic) and pristanic (2,6,10,14-tetramethylpentadecanoic) acids, in phytanic and pristanic acid moieties of neutral and polar lipids, and in esters of phytol. In addition, evidence is presented for the utilization of phytol to form 1-O-phytenyl-2-acyl glycerophosphatides. Radioactivity from [U-14-C]dihydrophytol was found in free phytanic and pristanic acids, the corresponding acyl groups of neutral and polar lipids, esters of dihydrophytol and 1-O-phytanyl-2-acyl glycerophosphatides. Incorporation of either substrate into O-alkylglycerols was very low, and labeled branched-chain alk-1-enylglycerols could not be detected.
将[U-14-C]叶绿醇（3,7,11,15-四甲基十六碳-2-烯-1-醇）和[U-14-C]二氢叶绿醇（3,7,11,15-四甲基十六烷醇）脑内注射给18日龄大鼠，6小时和24小时后测定放射性掺入脑脂质的情况。发现[U-14-C]叶绿醇的放射性存在于游离的植酸（3,7,11,15-四甲基十六碳-2-烯酸）、植烷酸（3,7,11,15-四甲基十六烷酸）和降植烷酸（2,6,10,14-四甲基十五烷酸）中，存在于中性和极性脂质的植烷酸和降植烷酸部分以及叶绿醇酯中。此外，还提供了叶绿醇用于形成1-O-植烷基-2-酰基甘油磷脂的证据。[U-14-C]二氢叶绿醇的放射性存在于游离的植烷酸和降植烷酸、中性和极性脂质的相应酰基、二氢叶绿醇酯以及1-O-植烷基-2-酰基甘油磷脂中。两种底物掺入O-烷基甘油的量非常低，且未检测到标记的支链链烯基甘油。
