与多发性骨髓瘤相关的铜在眼部的沉积。
Ocular deposition of copper associated with multiple myeloma.
作者信息
Hawkins A S, Stein R M, Gaines B I, Deutsch T A
机构信息
Department of Ophthalmology, Rush Medical College of Rush University, 1653 West Congress Parkway, Chicago, IL 60612, USA.
出版信息
Am J Ophthalmol. 2001 Feb;131(2):257-9. doi: 10.1016/s0002-9394(00)00657-7.
PURPOSE
To report a case of hypercupremia with deposits in both eyes on the Descemet's membrane, surface of the iris, and lens capsule associated with multiple myeloma.
METHOD
Case report.
RESULTS
A 64-year-old white woman had metallic deposits in both eyes on the central Descemet's membrane, surface of the iris, and the anterior and posterior lens capsule. A systemic examination revealed an elevated serum copper, normal serum ceruloplasmin, and an increased level of total protein and IgG kappa gammaglobulin. Based on these results, she was diagnosed with multiple myeloma.
CONCLUSIONS
Copper deposits on the Descemet's membrane, surface of the iris, and lens capsule may be the first sign of multiple myeloma.
目的
报告一例伴有双眼后弹力层、虹膜表面及晶状体囊膜沉积的高铜血症病例，该病例与多发性骨髓瘤相关。
方法
病例报告。
结果
一名64岁白人女性双眼中央后弹力层、虹膜表面以及晶状体前后囊膜均有金属沉积。全身检查显示血清铜升高、血清铜蓝蛋白正常，总蛋白和IgG κ球蛋白水平升高。基于这些结果，她被诊断为多发性骨髓瘤。
结论
后弹力层、虹膜表面及晶状体囊膜上的铜沉积可能是多发性骨髓瘤的首个体征。
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