Thestrup-Pedersen K
Immunology. 1975 Feb;28(2):343-8.
In two consecutive studies, eighteen and forty-one normal subjects were given a standard tuberculin skin test of 1 tuberculin unit (0.02 mug of PPD). Two days later another skin test was given. Readings of the skin reactions showed that subjects exhibiting strongly positive skin reactions in their primary skin tests showed a significantly smaller indurations in their primary skin tests tended to have equal or larger areas of induration after the secondary skin tests. These observations are discussed in relation to the possible existence of regulatory mechanisms of cell-mediated immune reactions.
在两项连续的研究中，分别对18名和41名正常受试者进行了1个结核菌素单位（0.02微克纯蛋白衍生物）的标准结核菌素皮肤试验。两天后进行了另一次皮肤试验。皮肤反应的读数显示，在初次皮肤试验中表现出强阳性皮肤反应的受试者，其初次皮肤试验中的硬结明显较小，而初次皮肤试验中硬结较小的受试者在二次皮肤试验后的硬结面积往往相等或更大。结合细胞介导免疫反应调节机制可能存在的情况对这些观察结果进行了讨论。
