Machová E, Kogan G, Chorvatovicová D, Sandula J
Institute of Chemistry, Slovak Academy of Sciences, Bratislava, Slovak Republic.
Ultrason Sonochem. 1999 Mar;6(1-2):111-4. doi: 10.1016/s1350-4177(98)00024-8.
Sonication was effective for the depolymerization of carboxymethylated chitin-glucan complex (CM-CG) isolated from the cell wall of Aspergillus niger. After 10 min of sonication and subsequent gel filtration, two samples (CM-CG(I) and CM CG(II)) with significantly distinct molecular weights (660 kDa and 19 kDa, respectively) and different nitrogen contents (3.02 and 1.69%) were obtained. CM-CG(II) with lower Mw was also effective against cyclophosphamide mutagenicity by oral administration in mice.
