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日本人群中阿尔茨海默病、血管性痴呆和路易体痴呆的患病率。

Prevalence of Alzheimer's disease, vascular dementia and dementia with Lewy bodies in a Japanese population.

作者信息

Yamada T, Hattori H, Miura A, Tanabe M, Yamori Y

机构信息

Department of Internal Medicine and Health Care, Fukuoka University, School of Medicine, Japan.

出版信息

Psychiatry Clin Neurosci. 2001 Feb;55(1):21-5. doi: 10.1046/j.1440-1819.2001.00779.x.

Abstract

We studied the prevalence of dementing disorders in a rural town of Japan (Amino-cho), using a door-to-door two-phase design. Of the 170 persons screened as having cognitive impairment, 142 cases were diagnosed as having dementia. The prevalence (cases/100 aged 65 years older) was 3.8 for all types of dementia, 2.1 for Alzheimer's disease (AD), 1.0 for vascular dementia (VD) and 0.7 for other types of dementia. Among other types of dementia, there were four male patients with dementia with Lewy bodies (prevalence: 0.1), but no patients with frontotemporal lobar degeneration. The overall prevalence was higher in women for AD, while that of VD was the same in both sexes. With results similar to many previous studies in Western countries and some recent surveys in Japan, the present sudy clearly showed that AD is more prevalent than VD.

摘要

我们采用逐户访问的两阶段设计,对日本一个乡村小镇(网代町)的痴呆症患病率进行了研究。在筛查出有认知障碍的170人中,有142例被诊断为患有痴呆症。各类痴呆症的患病率(每100名65岁及以上老人中的病例数)为3.8,阿尔茨海默病(AD)为2.1,血管性痴呆(VD)为1.0,其他类型痴呆症为0.7。在其他类型痴呆症中,有4名男性路易体痴呆患者(患病率:0.1),但没有额颞叶痴呆患者。AD的总体患病率女性高于男性,而VD在两性中相同。本研究结果与西方国家此前的许多研究以及日本最近的一些调查结果相似,清楚地表明AD比VD更普遍。

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