Eckstein F, Winzheimer M, Hohe J, Englmeier K H, Reiser M
Musculoskeletal Research Group, Institute of Anatomy, Ludwig-Maximilians-Universität, Pettenkoferstr. 11, Munich, D 80336, Germany.
Osteoarthritis Cartilage. 2001 Feb;9(2):101-11. doi: 10.1053/joca.2000.0365.
To determine the range and variability of the cartilage volume, thickness, and articular surface areas in the knee joints of healthy male subjects, the association of these parameters within and between the knee joint cartilage plates, and their correlation with anthropometric variables.
The right knees of 27 individuals (age 23 to 64 years) without cartilage damage were examined. Sagittal magnetic resonance imaging was with a fat-suppressed gradient echo sequence (resolution 2 x 0.31 x 0.31 mm(3)), quantitative parameters being computed for all cartilage plates.
The total knee joint cartilage volume ranged from 16.6 to 31.4 ml, the size of the articular surfaces from 102 to 163 cm(2), and the mean cartilage thickness from 1.57 to 2.43 mm. The mean and maximal cartilage thickness were highest in the patella (2.76 and 5.72 mm). There was a significant correlation of the cartilage volume with the mean thickness (R=0.80) and with the joint surface areas (R=0.56), but not between the thickness and surface area (R=0.37). The association among the patella, tibia, and femur was 0.16 to 0.72 for volumes, 0.08 to 0.78 for thickness, and 0.24 to 0.62 for surfaces. The knee joint cartilage volume and the surface areas were significantly associated with the body height (R=0.51 and 0.57), but not the cartilage thickness (R=0.22).
There is a surprisingly high variability of the quantitative distribution of cartilage within the knee joint, with only moderate correlations between knee joint cartilage plates, and this variability cannot be adequately predicted based on anthropometric variables.
确定健康男性受试者膝关节软骨体积、厚度和关节表面积的范围及变异性，这些参数在膝关节软骨板内及之间的关联，以及它们与人体测量学变量的相关性。
对27名无软骨损伤的个体（年龄23至64岁）的右膝进行检查。矢状面磁共振成像采用脂肪抑制梯度回波序列（分辨率2×0.31×0.31 mm³），计算所有软骨板的定量参数。
膝关节软骨总体积在16.6至31.4 ml之间，关节表面积在102至163 cm²之间，平均软骨厚度在1.57至2.43 mm之间。髌骨的平均和最大软骨厚度最高（分别为2.76和5.72 mm）。软骨体积与平均厚度（R = 0.80）和关节表面积（R = 0.56）显著相关，但厚度与表面积之间无显著相关性（R = 0.37）。髌骨、胫骨和股骨之间的体积关联为0.16至0.72，厚度关联为0.08至0.78，表面积关联为0.24至0.62。膝关节软骨体积和表面积与身高显著相关（R = 0.51和0.57），但与软骨厚度无关（R = 0.22）。
膝关节内软骨的定量分布存在惊人的高变异性，膝关节软骨板之间只有中等程度的相关性，且这种变异性无法基于人体测量学变量充分预测。
