A Ras by any other name.
作者信息
Bar-Sagi D
机构信息
Department of Molecular Genetics and Microbiology, State University of New York at Stony Brook, Stony Brook, New York 11794, USA.
出版信息
Mol Cell Biol. 2001 Mar;21(5):1441-3. doi: 10.1128/MCB.21.5.1441-1443.2001.
Abstract
摘要
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A Ras by any other name.换个名字的Ras。
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本文引用的文献
1
Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development.单独或联合对H-ras和N-ras进行靶向基因组破坏，揭示了这两个基因座对小鼠生长和发育并非必需。
Mol Cell Biol. 2001 Mar;21(5):1444-52. doi: 10.1128/MCB.21.5.1444-1452.2001.
2
H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway.H-ras而非K-ras通过外排途径转运至质膜。
Mol Cell Biol. 2000 Apr;20(7):2475-87. doi: 10.1128/MCB.20.7.2475-2487.2000.
3
Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains.显性负性小窝蛋白通过破坏富含胆固醇的质膜结构域来抑制H-Ras功能。
Nat Cell Biol. 1999 Jun;1(2):98-105. doi: 10.1038/10067.
4
Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi.Ras的内膜运输：CAAX基序将蛋白质靶向内质网和高尔基体。
Cell. 1999 Jul 9;98(1):69-80. doi: 10.1016/S0092-8674(00)80607-8.
5
Four human ras homologs differ in their abilities to activate Raf-1, induce transformation, and stimulate cell motility.
J Biol Chem. 1999 Jun 11;274(24):17164-70. doi: 10.1074/jbc.274.24.17164.
6
Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase.Ras亚型在激活Raf-1和磷酸肌醇3激酶的能力上存在差异。
J Biol Chem. 1998 Sep 11;273(37):24052-6. doi: 10.1074/jbc.273.37.24052.
7
Ha-ras and N-ras regulate MAPK activity by distinct mechanisms in vivo.Ha-ras和N-ras在体内通过不同机制调节丝裂原活化蛋白激酶（MAPK）的活性。
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8
Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane.小窝蛋白，是一类用于在质膜上组织“预组装信号复合物”的支架蛋白家族。
J Biol Chem. 1998 Mar 6;273(10):5419-22. doi: 10.1074/jbc.273.10.5419.
9
Ras-GRF activates Ha-Ras, but not N-Ras or K-Ras 4B, protein in vivo.
J Biol Chem. 1998 Jan 16;273(3):1782-7. doi: 10.1074/jbc.273.3.1782.
10
K-ras is an essential gene in the mouse with partial functional overlap with N-ras.K-ras是小鼠中的一个必需基因，与N-ras存在部分功能重叠。
Genes Dev. 1997 Oct 1;11(19):2468-81. doi: 10.1101/gad.11.19.2468.
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