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眼睑条件反射所提示的小脑学习机制

Mechanisms of cerebellar learning suggested by eyelid conditioning.

作者信息

Medina J F, Nores W L, Ohyama T, Mauk M D

机构信息

Department of Neurobiology and Anatomy, University of Texas Medical School, Box 20708, Houston, TX 77225, USA.

出版信息

Curr Opin Neurobiol. 2000 Dec;10(6):717-24. doi: 10.1016/s0959-4388(00)00154-9.

Abstract

Classical eyelid conditioning has been used to great advantage in demonstrating that the cerebellum helps to improve movements through experience, and in identifying the underlying mechanisms. Results from recent studies support the hypotheses that learning occurs in both the cerebellar nucleus and cortex, and that these sites make different contributions. Specifically, results indicate that the cerebellar cortex is responsible for temporally specific learning. A combination of experimental and computational studies has been important for arriving at these conclusions, which seem to be applicable to the broad range of movements to which the cerebellum contributes.

摘要

经典眼睑条件反射在证明小脑有助于通过经验改善运动以及确定潜在机制方面发挥了巨大作用。最近的研究结果支持了以下假设:学习发生在小脑核和皮质中,并且这些部位发挥着不同的作用。具体而言,结果表明小脑皮质负责时间特异性学习。实验研究和计算研究相结合对于得出这些结论很重要,这些结论似乎适用于小脑所参与的广泛运动。

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