Rezai H R, Ardehali S, Gettner S
Ann Trop Med Parasitol. 1975 Mar;69(1):29-33. doi: 10.1080/00034983.1975.11686981.
The growth inhibition activity of normal human, dog, rabbit, guinea pig, rat, sheep, cat, mouse and chicken sera was quantified against Leishmania enriettii and Leishmania tropica. The pattern of anti-L. enriettii activity of various animal sera was somewhat different from that observed in L. tropica. Against L. enriettii, mouse serum was inactive, and against L. tropica rat and mouse sera were inactive. All the other animal sera tested had growth inhibition activity on both leishmanias. This growth-inhibiting factor was found to be heat-labile, complement dependent, adsorbable by the specific organism and non-dialyzable. Only the first few subcultures of leishmania were affected by the active sera.
对来自正常人、狗、兔子、豚鼠、大鼠、绵羊、猫、小鼠和鸡的血清针对英氏利什曼原虫和热带利什曼原虫的生长抑制活性进行了定量分析。各种动物血清针对英氏利什曼原虫的活性模式与针对热带利什曼原虫所观察到的模式有所不同。针对英氏利什曼原虫，小鼠血清无活性；针对热带利什曼原虫，大鼠和小鼠血清无活性。所测试的所有其他动物血清对两种利什曼原虫均具有生长抑制活性。发现这种生长抑制因子对热不稳定、依赖补体、可被特定生物体吸附且不可透析。只有利什曼原虫的最初几代传代培养物受到活性血清的影响。
