Baron R, Wasner G
Klinik für Neurologie, Christian-Albrechts-Universität Kiel, Niemannsweg 147, Kiel 24105, Germany.
Curr Pain Headache Rep. 2001 Apr;5(2):114-23. doi: 10.1007/s11916-001-0079-x.
Complex regional pain syndromes (CRPS) (formerly reflex sympathetic dystrophy and causalgia) are neuropathic pain conditions that are initiated by an extremity trauma or peripheral nerve lesion. Clinical definition and scientific understanding of CRPS are still evolving; however, both the clinical picture and therapeutic options are significantly influenced by a dysfunction of the sympathetic nervous system. Recent investigations suggest functional central abnormalities and a peripheral inflammatory component in the pathophysiology of CRPS. Interdisciplinary treatment includes physical, pharmacologic, and invasive interventional therapy, as well as stimulation techniques.
复杂性区域疼痛综合征（CRPS）（以前称为反射性交感神经营养不良和灼痛）是由肢体创伤或周围神经损伤引发的神经性疼痛病症。对CRPS的临床定义和科学认识仍在不断发展；然而，其临床表现和治疗选择均受到交感神经系统功能障碍的显著影响。最近的研究表明，CRPS的病理生理学中存在功能性中枢异常和外周炎症成分。跨学科治疗包括物理治疗、药物治疗、侵入性介入治疗以及刺激技术。
