粪便念珠菌与腹泻。
Faecal candida and diarrhoea.
作者信息
Forbes D, Ee L, Camer-Pesci P, Ward P B
机构信息
Department of Paediatrics, University of Western Australia, Princess Margaret Hospital for Children, GPO Box D184, Perth, Western Australia, 6001.
出版信息
Arch Dis Child. 2001 Apr;84(4):328-31. doi: 10.1136/adc.84.4.328.
BACKGROUND
Candida species are frequently isolated from stools of children with diarrhoea but are not proven enteropathogens. It is hypothesised that faecal candida causes diarrhoea.
AIMS
To determine the prevalence of faecal candida in childhood diarrhoea and the relation between faecal yeasts and diarrhoea.
METHODS
Comparison of clinical and laboratory data, including quantitative stool culture for yeasts from 107 children hospitalised with diarrhoea and 67 age matched controls without diarrhoea.
RESULTS
Yeast species, predominantly candida, were identified in the stools of 43 children (39%) with diarrhoea and 26 (36%) without diarrhoea. The concentration of candida was positively associated with recent antibiotic use (p = 0.03) and with the presence of another enteric pathogen (p < 0.005), but not with patient age, nutritional status, or duration of diarrhoea.
CONCLUSION
Candida species do not cause childhood diarrhoea in well nourished children.
背景
念珠菌属常从腹泻儿童的粪便中分离出来，但尚未被证实为肠道病原体。据推测，粪便念珠菌会导致腹泻。
目的
确定儿童腹泻中粪便念珠菌的患病率以及粪便酵母菌与腹泻之间的关系。
方法
比较临床和实验室数据，包括对107名因腹泻住院的儿童和67名年龄匹配的无腹泻对照儿童进行粪便酵母菌定量培养。
结果
在43名（39%）腹泻儿童和26名（36%）无腹泻儿童的粪便中鉴定出酵母菌种，主要为念珠菌。念珠菌的浓度与近期使用抗生素（p = 0.03）以及另一种肠道病原体的存在（p < 0.005）呈正相关，但与患者年龄、营养状况或腹泻持续时间无关。
结论
在营养良好的儿童中，念珠菌属不会导致儿童腹泻。
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