Auerbach R, Arensman R, Kubai L, Folkman J
Int J Cancer. 1975 Feb 15;15(2):241-5. doi: 10.1002/ijc.2910150209.
The effect of irradiation of tumors on their ability to induce vascular responses (angiogenesis) was studied. Rat Walker carcino-sarcoma 256, rabbit V2 carcinoma, mouse (C57B1) melanoma and mouse (129) teratoma (OTT 6050, 100K) were irradiated with up to 5000R, then grafted either to the chicken chorioallantoic membrane or intracorneally into adult rabbits to assess competence to provoke angiogenesis. For all tumors and both assay systems the results were similar: irradiation did not interfere with tumor-induced vascular responses.
研究了肿瘤照射对其诱导血管反应（血管生成）能力的影响。将大鼠沃克癌肉瘤256、兔V2癌、小鼠（C57B1）黑色素瘤和小鼠（129）畸胎瘤（OTT 6050, 100K）照射高达5000伦琴，然后移植到鸡绒毛尿囊膜上或角膜内植入成年兔体内，以评估引发血管生成的能力。对于所有肿瘤和两种检测系统，结果相似：照射并未干扰肿瘤诱导的血管反应。
