Fiedler H P, Krastel P, Müller J, Gebhardt K, Zeeck A
Mikrobiologisches Institut, Universität Tübingen, Germany.
FEMS Microbiol Lett. 2001 Mar 15;196(2):147-51. doi: 10.1111/j.1574-6968.2001.tb10556.x.
Enterobactin is described in the literature as the typical iron-chelating compound (siderophore) produced by bacteria of the family Enterobacteriaceae. In the course of a HPLC with diode array detection screening programme for detection of novel secondary metabolites, enterobactin, its biosynthetic precursor 2,3-dihydroxy-N-benzoylserine and its linear dimer and trimer condensation products were found to be produced by two Streptomyces strains besides the trihydroxamate-type siderophores desferri-ferrioxamine B and E.
文献中描述肠杆菌素是肠杆菌科细菌产生的典型铁螯合化合物（铁载体）。在一项采用二极管阵列检测的高效液相色谱筛选程序中，用于检测新型次生代谢产物，结果发现除了三亚胺肟型铁载体去铁铁胺B和E外，两种链霉菌菌株还产生了肠杆菌素、其生物合成前体2,3-二羟基-N-苯甲酰丝氨酸及其线性二聚体和三聚体缩合产物。
