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1990年至1998年间德国南部失明的发病率。

Incidence of blindness in southern Germany between 1990 and 1998.

作者信息

Trautner C, Haastert B, Giani G, Berger M

机构信息

University of Bielefeld, School of Public Health, Germany.

出版信息

Diabetologia. 2001 Feb;44(2):147-50. doi: 10.1007/s001250051592.

Abstract

AIMS/HYPOTHESIS: A reduction of diabetes-related blindness by at least one third was declared a primary objective for Europe in 1989 (St. Vincent Declaration). To ascertain a potential change of incidence rates, we collected data on blindness in a German district (population: about 5 million) over 9 years.

METHODS

We obtained complete lists of newly registered blindness-allowance recipients between 1990 and 1998 and population data on Württemberg-Hohenzollern, Germany. We estimated incidence rates of blindness in the general population and the diabetic population. To ascertain any time trend, we applied Poisson regression models.

RESULTS

There were 6371 newly registered blindness allowance recipients (1990-1998). Of these 67% were women and 27 % had diabetes. Mean age was 71.7 years. Standardised results in the diabetic population (incidence rates per 100,000 person-years; standard: diabetic population; 95 % CI): 1990: 72 (61;82); 1991: 88 (76;100); 1992: 77 (67;88); 1993: 82 (71;93); 1994: 62 (53;72); 1995: 82 (71;93); 1996: 70 (60;80); 1997: 69 (59;79); 1998: 59 (49;68). The Poisson model estimated a 3 % decrease of incident blindness in the diabetic population for each year (Relative risk per year 0.97; CI: 0.95; 0.99). No significant change could be observed in the non-diabetic population (Relative risk: 0.99; CI: 0.98; 1.00). Relative risks for each year varied between sub-groups according to sex, diabetic status and cause of blindness between 0.94 and 1.01.

CONCLUSION/INTERPRETATION: A slight reduction of incident blindness could be shown but a reduction by one third has not been reached. Several possible sources of bias in the data have to be considered.

摘要

目的/假设:1989年欧洲宣布将糖尿病相关失明率降低至少三分之一作为主要目标(圣文森特宣言)。为确定发病率的潜在变化,我们收集了德国一个地区(人口约500万)9年间失明情况的数据。

方法

我们获取了1990年至1998年间新登记的失明津贴领取者的完整名单以及德国符腾堡 - 霍亨索伦的人口数据。我们估计了普通人群和糖尿病患者人群中的失明发病率。为确定任何时间趋势,我们应用了泊松回归模型。

结果

有6371名新登记的失明津贴领取者(1990 - 1998年)。其中67%为女性,27%患有糖尿病。平均年龄为71.7岁。糖尿病患者人群的标准化结果(每10万人年发病率;标准:糖尿病患者人群;95%置信区间):1990年:72(61;82);1991年:88(76;100);1992年:77(67;88);1993年:82(71;93);1994年:62(53;72);1995年:82(71;93);1996年:70(60;80);1997年:69(59;79);1998年:59(49;68)。泊松模型估计糖尿病患者人群中失明发病率每年下降3%(每年相对风险0.97;置信区间:0.95;0.99)。在非糖尿病患者人群中未观察到显著变化(相对风险:0.99;置信区间:0.98;1.00)。每年的相对风险在根据性别、糖尿病状态和失明原因划分的亚组之间在0.94至1.01之间变化。

结论/解读:可以显示失明发病率略有下降,但未达到三分之一的降幅。必须考虑数据中几个可能的偏差来源。

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