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从羊角拗中分离得到的一种吲哚生物碱——羊角拗碱的抗真菌活性。

Antifungal activity of venenatine, an indole alkaloid isolated from Alstonia venenata.

作者信息

Singh U P, Sarma B K, Mishra P K, Ray A B

机构信息

Department of Mycology and Plant Pathology, Institute of Agricultural Sciences, Banaras Hindu University, Varanasi 221 005, India.

出版信息

Folia Microbiol (Praha). 2000;45(2):173-6. doi: 10.1007/BF02817419.

DOI:10.1007/BF02817419
PMID:11271828
Abstract

The indole alkaloid venenatine exhibited antifungal activity against some plant pathogenic and saprophytic fungi. Venenatine in an aqueous acetic acid solution inhibited spore germination of all the 10 tested fungi, Fusarium udum, Alternaria brassicicola, Ustilago cynodontis and Aspergillus flavus showed an especially high sensitivity towards this compound, exhibiting germination levels below 10%. The spore germination and colony development of the parasitic fungus Erysiphe pisi, which causes powdery mildew in pea (Pisum sativum), on excised leaves of pea was also significantly affected. Pre-inoculation rather than post inoculation treatment of the leaves was more inhibitory against spore germination and colony development.

摘要

吲哚生物碱毒黎碱对一些植物病原真菌和腐生真菌表现出抗真菌活性。毒黎碱在乙酸水溶液中抑制了所有10种受试真菌的孢子萌发,其中乌德镰孢菌、芸苔链格孢菌、狗牙根黑粉菌和黄曲霉对该化合物表现出特别高的敏感性,萌发率低于10%。寄生真菌豌豆白粉菌可导致豌豆(豌豆属)白粉病,其在豌豆离体叶片上的孢子萌发和菌落发育也受到显著影响。叶片的接种前而非接种后处理对孢子萌发和菌落发育的抑制作用更强。

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本文引用的文献

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Antifungal diterpenoid alkaloids from Delphinium denudatum.露蕊乌头中的抗真菌二萜生物碱。
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Crystal structures of 1-benzene-sulfon-yl-2-methyl-3-(4-nitro-benzoyl)-2,3-di-hydro-1-indole and 1-benzene-sulfon-yl-2-methyl-3-[(thio-phen-2-yl)carbon-yl]-2,3-di-hydro-1-indole.1-苯磺酰基-2-甲基-3-(4-硝基苯甲酰基)-2,3-二氢-1-吲哚和1-苯磺酰基-2-甲基-3-[(噻吩-2-基)羰基]-2,3-二氢-1-吲哚的晶体结构
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