Sharma A K, Gupta R, Gupta H P, Singh A K
Department of Nephrology, Monilek Hospital and Research Center, Jawahar Nagar, Jaipur-302 004.
J Assoc Physicians India. 2000 Apr;48(4):400-1.
We studied acute haemodynamic effects of pan masala (powdered mixture of areca nut, slaked lime, catechu, and condiments) in healthy volunteers.
Fifty one males (mean age 28.6 +/- 10 years) were evaluated. One pouch (4 g) of pan masala without tobacco was given to each subject under fasting state and effects on pulse and blood pressure (BP) recorded.
At baseline the pulse rate was 75.1 +/- 9.0 per minute, systolic BP was 119.1 +/- 10.8 mm Hg, and diastolic BP was 78.0 +/- 7.5. The pulse rate increased to 87.5 +/- 11.4 at ten minutes (+16.9 +/- 12.6%, p < 0.001) and fell to 76.7 +/- 9.1 at 30 minutes (p = ns). Systolic BP increased to 122.3 +/- 11.7 mm Hg at 10 minutes (+2.73 +/- 5.1%, p < 0.001) and was 120.8 +/- 10.8 at 30 minutes; while diastolic BP was 80.8 +/- 7.3 at 10 minutes (+3.83 +/- 6.1%, p < 0.001) and 79.4 +/- 7.6 at 30 minutes.
Pan masala intake causes acute increase in pulse and BP.
我们研究了嚼烟（槟榔、熟石灰、儿茶和调味品的粉末混合物）对健康志愿者的急性血流动力学影响。
对51名男性（平均年龄28.6±10岁）进行评估。在禁食状态下，给每位受试者一袋（4克）不含烟草的嚼烟，并记录对脉搏和血压（BP）的影响。
基线时，脉搏率为每分钟75.1±9.0次，收缩压为119.1±10.8毫米汞柱，舒张压为78.0±7.5。10分钟时脉搏率增至87.5±11.4次（+16.9±12.6%，p<0.001），30分钟时降至76.7±9.1次（p=无统计学意义）。收缩压在10分钟时升至122.3±11.7毫米汞柱（+2.73±5.1%，p<0.001），30分钟时为120.8±10.8；而舒张压在10分钟时为80.8±7.3（+3.83±6.1%，p<0.001），30分钟时为79.4±7.6。
摄入嚼烟会导致脉搏和血压急性升高。
