HL - A 5与体外对链球菌抗原的免疫反应性的关联。
Association of HL-A 5 and immune responsiveness in vitro to streptococcal antigens.
作者信息
Greenberg L J, Gray E D, Yunis E J
出版信息
J Exp Med. 1975 May 1;141(5):935-43. doi: 10.1084/jem.141.5.935.
Abstract
Lymphocytes, from randomly selected individuals having normal immune function, when incubated in vitro with varying concentrations of streptococcal antigens, responded in three ways: (a) response over the entire antigen concentration range, i.e., responders; (b) low response to only the highest antigen concentrations; and (c) no response at any antigen concentration. Frequency distribution analysis of these groups indicated that a significant association occurred between the ability to respond and HL-A 5.
摘要
从具有正常免疫功能的随机选择个体中获取的淋巴细胞，当在体外与不同浓度的链球菌抗原一起孵育时，会有三种反应方式：(a) 在整个抗原浓度范围内都有反应，即反应者；(b) 仅对最高抗原浓度有低反应；以及 (c) 在任何抗原浓度下都无反应。对这些组的频率分布分析表明，反应能力与HL - A 5之间存在显著关联。
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