HL - A 5与体外对链球菌抗原的免疫反应性的关联。
Association of HL-A 5 and immune responsiveness in vitro to streptococcal antigens.
作者信息
Greenberg L J, Gray E D, Yunis E J
出版信息
J Exp Med. 1975 May 1;141(5):935-43. doi: 10.1084/jem.141.5.935.
Abstract
Lymphocytes, from randomly selected individuals having normal immune function, when incubated in vitro with varying concentrations of streptococcal antigens, responded in three ways: (a) response over the entire antigen concentration range, i.e., responders; (b) low response to only the highest antigen concentrations; and (c) no response at any antigen concentration. Frequency distribution analysis of these groups indicated that a significant association occurred between the ability to respond and HL-A 5.
摘要
从具有正常免疫功能的随机选择个体中获取的淋巴细胞，当在体外与不同浓度的链球菌抗原一起孵育时，会有三种反应方式：(a) 在整个抗原浓度范围内都有反应，即反应者；(b) 仅对最高抗原浓度有低反应；以及 (c) 在任何抗原浓度下都无反应。对这些组的频率分布分析表明，反应能力与HL - A 5之间存在显著关联。
相似文献
1
Association of HL-A 5 and immune responsiveness in vitro to streptococcal antigens.HL - A 5与体外对链球菌抗原的免疫反应性的关联。
J Exp Med. 1975 May 1;141(5):935-43. doi: 10.1084/jem.141.5.935.
2
HL-A LD (lymphocyte defined) typing: a rapid assay with primed lymphocytes.HL-A LD（淋巴细胞定义）分型：一种用致敏淋巴细胞的快速检测法。
Science. 1975 Jun 27;188(4195):1308-10. doi: 10.1126/science.124948.
3
4
Biologic activity of transfer factor tested in vitro with cord blood lymphocytes.用脐血淋巴细胞在体外测试转移因子的生物活性。
Int Arch Allergy Appl Immunol. 1977;54(3):269-80. doi: 10.1159/000231836.
5
6
Suppressor T cells control the HLA-linked low responsiveness to streptococcal antigen in man.
Nature. 1983 Mar 3;302(5903):67-9. doi: 10.1038/302067a0.
7
Parameters for effective use of synthetic double stranded polynucleotides in the amplification of immunologically induced lymphocyte tritiated thymidine incorporation.
Cell Immunol. 1974 Mar 30;11(1-3):47-56. doi: 10.1016/0008-8749(74)90005-7.
8
In vitro lymphocyte responsiveness of human subjects receiving azathioprine.接受硫唑嘌呤的人类受试者的体外淋巴细胞反应性。
Int Arch Allergy Appl Immunol. 1971;41(2):428-33. doi: 10.1159/000230536.
9
Lymphocyte antigenicity loss with retention of responsiveness.淋巴细胞抗原性丧失但反应性保留。
Science. 1974 Apr 26;184(4135):464-6. doi: 10.1126/science.184.4135.464.
10
Stimulation of lymphocytes by antigen in microplate cultures; absence of an effect of transfer factor in vitro.微量培养板中抗原对淋巴细胞的刺激作用；转移因子在体外无作用
Clin Exp Immunol. 1976 Mar;23(3):499-506.
引用本文的文献
1
The relationship between genetics and environment in the pathogenesis of rheumatic diseases.遗传因素与环境因素在风湿性疾病发病机制中的关系。
West J Med. 1979 Sep;131(3):205-18.
2
Pathogenesis of acute rheumatic fever and rheumatic heart disease: evasive after half a century of clinical, epidemiological, and laboratory investigation.急性风湿热和风湿性心脏病的发病机制：经过半个世纪的临床、流行病学及实验室研究仍未明确。
Heart. 2005 Jan;91(1):3-4. doi: 10.1136/hrt.2004.034744.
3
Sydenham chorea: clinical, EEG, MRI and SPECT findings in the early stage of the disease.
J Neurol. 1993 Feb;240(2):121-3. doi: 10.1007/BF00858729.
4
Role of macrophages in T lymphocyte response to Candida allergen in man with special reference to HLA-D and DR.巨噬细胞在人类对念珠菌变应原的T淋巴细胞反应中的作用，特别涉及HLA - D和DR。
Clin Exp Immunol. 1981 Jul;45(1):152-7.
5
HLA restriction of human cytotoxic T cells.人类细胞毒性T细胞的HLA限制
Springer Semin Immunopathol. 1980 May;3(1):3-22. doi: 10.1007/BF00199923.
6
Cellular immune responses to extracellular streptococcal products in rheumatic heart disease.风湿性心脏病中针对细胞外链球菌产物的细胞免疫反应。
J Clin Invest. 1981 Sep;68(3):665-71. doi: 10.1172/jci110301.
7
Immunogenetics of response to a purified antigen from group A streptococci. I. Complex segregation analysis.对A组链球菌纯化抗原反应的免疫遗传学。I. 复杂分离分析。
Immunogenetics. 1980;11(2):145-6. doi: 10.1007/BF01567780.
8
HLA-B8 and cell-mediated immunity to gluten.人类白细胞抗原B8与针对麸质的细胞介导免疫
Gut. 1981 Aug;22(8):633-6. doi: 10.1136/gut.22.8.633.
9
Detection of immune complexes in acute rheumatic fever and their relationship to HLA-B5.急性风湿热中免疫复合物的检测及其与HLA - B5的关系。
J Clin Invest. 1980 Jan;65(1):136-45. doi: 10.1172/JCI109643.
10
Immunopathogenesis of rheumatic fever and rheumatic heart disease-current concepts.风湿热和风湿性心脏病的免疫发病机制——当前概念
Indian J Pediatr. 1982 Nov-Dec;49(401):849-62. doi: 10.1007/BF02976980.
本文引用的文献
1
The inhibition of streptococcal desoxyribonuclease by rabbit and human antisera.兔抗血清和人抗血清对链球菌脱氧核糖核酸酶的抑制作用。
J Exp Med. 1949 Dec;90(6):543-53. doi: 10.1084/jem.90.6.543.
2
A simple micro cytotoxicity test.一种简单的微量细胞毒性试验。
Transplantation. 1969 Mar;7(3):220-3. doi: 10.1097/00007890-196903000-00023.
3
The effect of histocompatibility-2 type on response to friend leukemia virus in mice.组织相容性-2类型对小鼠对Friend白血病病毒反应的影响。
J Exp Med. 1968 Mar 1;127(3):465-73. doi: 10.1084/jem.127.3.465.
4
Autoimmune murine thyroiditis relation to histocompatibility (H-2) type.自身免疫性小鼠甲状腺炎与组织相容性（H-2）类型的关系。
Science. 1971 Dec 10;174(4014):1137-9. doi: 10.1126/science.174.4014.1137.
5
Disturbance of HL-A antigen frequency in Psoriasis.银屑病中HL-A抗原频率的紊乱。
N Engl J Med. 1972 Oct 12;287(15):740-3. doi: 10.1056/NEJM197210122871504.
6
Histocompatibility (HL-A) antigens associated with psoriasis.与银屑病相关的组织相容性（HL-A）抗原。
N Engl J Med. 1972 Oct 12;287(15):738-40. doi: 10.1056/NEJM197210122871503.
7
Lymphocyte stimulation by a glycopeptide isolated from Streptococcus pyogenes C203S. I. Isolation and partial purification.由化脓性链球菌C203S分离出的一种糖肽对淋巴细胞的刺激作用。I. 分离与部分纯化。
Cell Immunol. 1970 Nov;1(5):476-87. doi: 10.1016/0008-8749(70)90036-5.
8
Cross-reactions between streptococcal M proteins and human transplantation antigens.链球菌M蛋白与人移植抗原之间的交叉反应。
Science. 1970 May 29;168(3935):1095-6. doi: 10.1126/science.168.3935.1095.
9
Genetic control of specific immune responses.特异性免疫反应的遗传控制。
Adv Immunol. 1969;11:31-74. doi: 10.1016/s0065-2776(08)60477-0.
10
The H-2 locus of the mouse: observations and speculations concerning its comparative genetics and its polymorphism.小鼠的H-2基因座：关于其比较遗传学和多态性的观察与推测。
Folia Biol (Praha). 1968;14(5):335-58.
Zotero 插件