使用类固醇和静脉注射免疫球蛋白治疗非典型急性播散性脑脊髓炎的疗效改善

Improvement of atypical acute disseminated encephalomyelitis with steroids and intravenous immunoglobulins.

作者信息

Straussberg R, Schonfeld T, Weitz R, Karmazyn B, Harel L

机构信息

Department of Pediatric Neurology, Schneider Children's Medical Center of Israel, Petach Tikvah, Israel.

出版信息

Pediatr Neurol. 2001 Feb;24(2):139-43. doi: 10.1016/s0887-8994(00)00229-0.

DOI:10.1016/s0887-8994(00)00229-0

PMID:11275464

Abstract

Acute disseminated encephalomyelitis is a demyelinating syndrome that occurs infrequently in children. Various treatment modalities, such as plasmapheresis or steroids or intravenous immunoglobulins (IVIG), have been prescribed. The article describes the results of combined IVIG and high-dose steroids given for 3 days in the treatment of a patient with atypical encephalomyelitis. The results suggest that this approach may be more beneficial than the application of either drug alone.

摘要

急性播散性脑脊髓炎是一种在儿童中不常发生的脱髓鞘综合征。已经采用了多种治疗方式，如血浆置换、类固醇或静脉注射免疫球蛋白（IVIG）。本文描述了对一名非典型脑脊髓炎患者联合使用IVIG和大剂量类固醇进行3天治疗的结果。结果表明，这种方法可能比单独使用任何一种药物更有益。