Golding J F, Mueller A G, Gresty M A
Department of Psychology, University of Westminster, London, United Kingdom.
Aviat Space Environ Med. 2001 Mar;72(3):188-92.
Low frequency translational oscillation can provoke motion sickness in land vehicles, ships and aircraft. Although controlled motion experiments indicate a progressive increase in nauseogenicity as frequency decreases toward 0.2 Hz, few data are available on the existence of a definite maximum nauseogenic potential of motion around 0.2 Hz, or decreased nauseogenicity below this frequency.
Nauseogenicity should be maximal around 0.2 Hz.
We selected 12 subjects for high motion sickness susceptibility, and they were exposed to horizontal sinusoidal motion (1.0 m.s(-2) peak acceleration) at 3 different frequencies (0.1, 0.2 and 0.4 Hz), at 1-wk intervals at the same time of day, according to a factorial design. Subjects were seated comfortably in the upright position with head erect. Fore-aft motion was through the body and head X-axis. Motion was stopped (motion endpoint) at moderate nausea or after 30 min.
The proportion of subjects experiencing moderate nausea was maximal at the intermediate frequency: 8/12 at 0.1 Hz, 12/12 at 0.2 Hz, 7/12 at 0.4 Hz. The mean time to motion endpoint was significantly (p < 0.01) shorter at the intermediate frequency: 18.0 min at 0.1 Hz; 11.2 min at 0.2 Hz; 20.2 min at 0.4 Hz. Similar frequency patterns emerged for other sickness ratings. The equivalent times to achieve moderate nausea using estimated values to correct for subjects who reached the 30 min time cut-off were: 22.7 min at 0.1 Hz; 11.2 min at 0.2 Hz; 28.1 min at 0.4 Hz.
A maximum nauseogenic potential around 0.2 Hz was substantiated.
低频平移振荡可在陆地车辆、船舶和飞机上引发晕动病。尽管受控运动实验表明，随着频率向0.2赫兹降低，致呕性会逐渐增加，但关于0.2赫兹左右运动是否存在明确的最大致呕潜力，或低于该频率时致呕性降低的数据却很少。
致呕性应在0.2赫兹左右达到最大值。
我们选择了12名晕动病易感性高的受试者，根据析因设计，让他们在一天中的同一时间，每隔1周，以3种不同频率（0.1、0.2和0.4赫兹）暴露于水平正弦运动（峰值加速度为1.0米·秒⁻²）中。受试者舒适地直立坐着，头部挺直。前后运动通过身体和头部的X轴进行。当出现中度恶心或30分钟后停止运动（运动终点）。
出现中度恶心的受试者比例在中间频率时最高：0.1赫兹时为8/12，0.2赫兹时为12/12，0.4赫兹时为7/12。达到运动终点的平均时间在中间频率时显著缩短（p < 0.01）：0.1赫兹时为18.0分钟；0.2赫兹时为11.2分钟；0.4赫兹时为20.2分钟。其他晕动病评级也出现了类似的频率模式。使用估计值对达到30分钟时间截止点的受试者进行校正后，达到中度恶心的等效时间为：0.1赫兹时为22.7分钟；0.2赫兹时为11.2分钟；0.4赫兹时为28.1分钟。
证实了0.2赫兹左右存在最大致呕潜力。
