Shneerson J, Wright J
Respiratory Support and Sleep Centre, Papworth Hospital, Papworth Everard, Cambridge, UK, CB3 8RE.
Cochrane Database Syst Rev. 2001;2001(1):CD002875. doi: 10.1002/14651858.CD002875.
Obstructive sleep apnoeas are due to transient closure of the upper airway during sleep and merge into hypopnoeas in which the airway narrows, but some airflow continues. They are due to the forces compressing the airway overcoming those which stabilise its patency. The commonest association is obesity in which fatty tissue is deposited around the airway. Exercise has been recommended as a method of losing weight, but other techniques which achieve this are also thought to improve symptoms due to sleep apnoeas. Sleep hygiene may alter the sleep structure and the control of the upper airway during sleep and thus promote its patency.
The objectives of this review are to determine whether weight loss, sleep hygiene and exercise are effective in the treatment of obstructive sleep apnoeas.
The Cochrane Airways Group Trials Register, MEDLINE, EMBASE, CINAHL and reference lists of review articles have been searched.
Randomised, single or double blind placebo controlled, either parallel group or crossover design studies of any of these interventions were to have been included.
No completed trials have been identified.
No randomised trial data were available for analysis.
REVIEWER'S CONCLUSIONS: There is a need for randomised controlled trials of these commonly used treatments in obstructive sleep apnoeas. These should identify which sub groups of patients with sleep apnoeas benefit most from each type of treatment and they should have clear and standardised outcome measures.
阻塞性睡眠呼吸暂停是由于睡眠期间上呼吸道短暂关闭,并发展为呼吸浅慢,即气道变窄但仍有一些气流通过。其原因是压缩气道的力量超过了维持气道通畅的力量。最常见的相关因素是肥胖,即气道周围有脂肪组织沉积。运动被推荐为一种减肥方法,但其他实现减肥的技术也被认为可以改善睡眠呼吸暂停引起的症状。睡眠卫生可能会改变睡眠结构以及睡眠期间对上呼吸道的控制,从而促进气道通畅。
本综述的目的是确定减肥、睡眠卫生和运动在阻塞性睡眠呼吸暂停治疗中是否有效。
检索了Cochrane气道组试验注册库、MEDLINE、EMBASE、CINAHL以及综述文章的参考文献列表。
纳入任何这些干预措施的随机、单盲或双盲安慰剂对照、平行组或交叉设计研究。
未识别出已完成的试验。
无随机试验数据可供分析。
需要对阻塞性睡眠呼吸暂停的这些常用治疗方法进行随机对照试验。这些试验应确定哪些睡眠呼吸暂停患者亚组从每种治疗类型中获益最大,并且应有明确和标准化的结局指标。