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[巨细胞病毒抗原血症检测作为三例胶原病患者巨细胞病毒感染早期诊断和治疗的有用工具]

[Cytomegalovirus antigenemia assay as a useful tool for early diagnosis and therapy for cytomegalovirus infections in three cases with collagen diseases].

作者信息

Tsuji T, Misumi M, Inoue Y, Ideguchi H, Okubo T, Ueda A, Ohno S, Hagiwara E, Aoki A, Ishigatsubo Y

机构信息

First Department of Internal Medicine, Yokohama City University School of Medicine.

出版信息

Nihon Rinsho Meneki Gakkai Kaishi. 2001 Feb;24(1):29-35. doi: 10.2177/jsci.24.29.

DOI:10.2177/jsci.24.29
PMID:11280898
Abstract

We report here three cases of collagen diseases with cytomegalovirus infections. (1) A 21-year-old female, who had been diagnosed as systemic lupus erythematosus, lupus nephritis and lupus peritonitis, had fever. Cytomegalovirus antigenemia (CMV-Ag) assay was 10/8 positive. (2) A 33-year-old female, who had been diagnosed as Wegener glanulomatosis, had fever and liver dysfunction. CMV-Ag assay was 933/896 positive. (3) A 64-year-old female, who had been diagnosed as microscopic polyangitis, had fever, liver dysfunction and pneumonia. CMV-Ag assay was 6/2 positive. They were considered to be complicated with CMV infections. We could make early diagnoses of CMV infection by using CMV-Ag assay and treat them with anti-CMV therapy effectively.

摘要

我们在此报告3例合并巨细胞病毒感染的胶原病病例。(1)一名21岁女性,曾被诊断为系统性红斑狼疮、狼疮性肾炎和狼疮性腹膜炎,出现发热症状。巨细胞病毒抗原血症(CMV-Ag)检测结果为10/8阳性。(2)一名33岁女性,曾被诊断为韦格纳肉芽肿,出现发热和肝功能障碍。CMV-Ag检测结果为933/896阳性。(3)一名64岁女性,曾被诊断为显微镜下多血管炎,出现发热、肝功能障碍和肺炎。CMV-Ag检测结果为6/2阳性。这些病例被认为合并了CMV感染。通过使用CMV-Ag检测,我们能够早期诊断CMV感染,并通过抗CMV治疗有效治疗这些患者。

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J Bras Nefrol. 2018 Jan-Mar;40(1):44-52. doi: 10.1590/2175-8239-JBN-3838. Epub 2018 Apr 26.