越南湄公河三角洲地区东威省伤寒热的流行病学情况。

The epidemiology of typhoid fever in the Dong Thap Province, Mekong Delta region of Vietnam.

作者信息

Lin F Y, Vo A H, Phan V B, Nguyen T T, Bryla D, Tran C T, Ha B K, Dang D T, Robbins J B

机构信息

National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

出版信息

Am J Trop Med Hyg. 2000 May;62(5):644-8. doi: 10.4269/ajtmh.2000.62.644.

DOI:10.4269/ajtmh.2000.62.644

PMID:11289678

Abstract

A population-based surveillance for typhoid fever was conducted in three rural communes of Dong Thap Province in southern Vietnam (population 28,329) for a 12-month-period starting on December 4, 1995. Cases of typhoid fever were detected by obtaining blood for culture from residents with fever > or = 3 days. Among 658 blood cultures, 56 (8.5%) were positive for Salmonella typhi with an overall incidence of 198 per 10(5) population per year. The peak occurrence was at the end of the dry season in March and April. The attack rate was highest among 5-9 year-olds (531/10(5)/year), and lowest in > 30 year-olds (39/10(5)/year). The attack rate was 358/10(5)/year in 2-4 year-olds. The isolation of S. typhi from blood cultures was highest (17.4%) in patients with 5 to 6 days of fever. Typhoid fever is highly endemic in Vietnam and is a significant disease in both preschool and school-aged children.

摘要

1995年12月4日起，在越南南部同塔省的三个乡村公社（人口28,329）开展了为期12个月的伤寒热人群监测。通过采集发热≥3天居民的血液进行培养来检测伤寒热病例。在658份血培养中，56份（8.5%）伤寒沙门氏菌呈阳性，总体发病率为每年每10万人口198例。发病高峰出现在3月和4月旱季结束时。发病率在5至9岁儿童中最高（每年531/10万），在30岁以上人群中最低（每年39/10万）。2至4岁儿童的发病率为每年358/10万。发热5至6天的患者血培养中伤寒沙门氏菌分离率最高（17.4%）。伤寒热在越南高度流行，在学龄前和学龄儿童中都是一种重要疾病。