Sweeney A P, Wyllie S G, Shalliker R A, Markham J L
Centre for Biostructural and Biomolecular Research, University of Western Sydney, Hawkesbury, NSW, 2753, Richmond, Australia.
J Ethnopharmacol. 2001 May;75(2-3):273-7. doi: 10.1016/s0378-8741(01)00176-3.
Twenty-eight extracts from 17 species of Australian native plants traditionally used as general anti-inflammatory medicines by Australian Aboriginal people were examined for inhibition of the enzyme xanthine oxidase (XO). The extracts from nine species were found to have more than 25% inhibition at a concentration of 100 microg/ml in the assay mixture. Extracts from three species Clerodendrum floribundum R. Br. (Verbenaceae), Eremophila maculata (Ker Gawler) (Myoporaceae) and Stemodia grossa Benth. (Scrophulariaceae) showed the greatest activity with inhibitions of 84, 61 and 57%, respectively, at 50 microg/ml, with four other species having more than 40% inhibitory activity at this concentration.
对澳大利亚原住民传统上用作一般抗炎药物的17种澳大利亚本土植物的28种提取物进行了检测，以研究其对黄嘌呤氧化酶（XO）的抑制作用。在测定混合物中，发现9种植物的提取物在浓度为100微克/毫升时具有超过25%的抑制率。三种植物的提取物，即多花臭牡丹（马鞭草科）、斑纹埃瑞木（苦槛蓝科）和粗茎泽米草（玄参科），在50微克/毫升时显示出最大活性，抑制率分别为84%、61%和57%，另外四种植物在该浓度下具有超过40%的抑制活性。
