Lin C C, Hsu Y F, Lin T C
Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Anticancer Res. 2001 Jan-Feb;21(1A):237-43.
Reactive oxygen species (ROS) react with biological molecules and destroy the structure of cells and eventually cause free radical-induced disease such as inflammation and cancer. Previous studies showed that an aqueus extract of Terminalia catappa L. exhibited superoxide radical scavenger activity and modification of mitomycin C-induced clasto-genicity. In order to investigate the multiple antioxidant effect of the tannin components of T. catappa L., their ability to prevent lipid peroxidation, superoxide formation and their free radical scavenging activity were evaluated. The results indicated that all of these components showed potent antioxidant activity. Punicalagin and punicalin were the most abundant components and had the strongest anti-oxidative effects of this group of tannins.
活性氧（ROS）与生物分子发生反应，破坏细胞结构，最终导致自由基引发的疾病，如炎症和癌症。先前的研究表明，榄仁树的水提取物具有超氧阴离子自由基清除活性，并能改变丝裂霉素C诱导的染色体断裂活性。为了研究榄仁树单宁成分的多种抗氧化作用，评估了它们预防脂质过氧化、超氧形成的能力及其自由基清除活性。结果表明，所有这些成分都表现出强大的抗氧化活性。石榴皮苷和石榴苷是该组单宁中含量最丰富的成分，具有最强的抗氧化作用。
