Lieberthal M M, Martens R A
Am J Dig Dis. 1975 May;20(5):469-74. doi: 10.1007/BF01070793.
An attempt was made to test the possible clinical application of the cholesterol-lowering effect of hydrophilic colloids. 10 patients with high mean serum cholesterol levels during a 3-week control period and 9 with normal mean levels were each fed 11.5 g daily of undiluted hydrophilic colloid for 5 weeks. Serum cholesterol decreased significantly in 8 of the 10 (80%) patients with control-period hypercholesteremia and 6 of the 9 (66 2/3%) with control-period normal levels. These findings tend to confirm the observation that a simple and commonly used type of medication for chronic constipation, particularly in the elderly, may be a useful adjunct in the management of hypercholesterolemia.
人们尝试测试亲水性胶体降胆固醇作用的可能临床应用。在为期3周的对照期内平均血清胆固醇水平较高的10名患者以及平均水平正常的9名患者，均每日服用11.5克未稀释的亲水性胶体，持续5周。在对照期患有高胆固醇血症的10名患者中，有8名（80%）血清胆固醇显著下降；在对照期胆固醇水平正常的9名患者中，有6名（66 2/3%）血清胆固醇显著下降。这些发现倾向于证实以下观察结果：一种简单且常用的治疗慢性便秘的药物，尤其是在老年人中，可能是治疗高胆固醇血症的有用辅助药物。
