Neal G W, Balm T K
Methodist Medical Center of Oak Ridge, Tenn.
South Med J. 1990 Oct;83(10):1131-7. doi: 10.1097/00007611-199010000-00005.
We investigated psyllium fiber supplementation as a means of enhancing the cholesterol-lowering effect of the phase I American Heart Association diet. Fifty-nine subjects with total serum cholesterol (TC) levels ranging from 5.56 to 10.24 mmol/L (215 to 396 mg/dL) were given a 2-month dietary lead-in followed by 3 months of diet only (29 subjects) or diet supplemented with 20.4 g of psyllium daily (30 subjects). Unlike women, men had a significant decrease in levels of both TC (-8.0%) and low-density lipoprotein cholesterol (LDL-C) (-10.1%) during the dietary lead-in. Psyllium supplementation resulted in an additional 5.5% reduction in the TC levels as compared to diet alone. Psyllium supplementation combined with dietary lead-in resulted in an overall 17.3% decrease in the TC and a 20.0% decrease in LDL-C for men, with decreases of 7.7% and 11.6%, respectively, for women. Psyllium effectively enhances the cholesterol-lowering effect of the phase I diet.
我们研究了补充车前子纤维作为增强美国心脏协会一期饮食降胆固醇效果的一种方法。59名血清总胆固醇（TC）水平在5.56至10.24 mmol/L（215至396 mg/dL）之间的受试者先进行了为期2个月的饮食导入期，随后3个月仅采用饮食干预（29名受试者）或饮食中每日补充20.4 g车前子纤维（30名受试者）。与女性不同，男性在饮食导入期TC水平（-8.0%）和低密度脂蛋白胆固醇（LDL-C）水平（-10.1%）均显著下降。与单纯饮食相比，补充车前子纤维使TC水平额外降低了5.5%。对于男性，补充车前子纤维与饮食导入期相结合使TC总体下降了17.3%，LDL-C下降了20.0%；对于女性，TC和LDL-C分别下降了7.7%和11.6%。车前子纤维能有效增强一期饮食的降胆固醇效果。
