Budson A E, Desikan R, Daffner K R, Schacter D L
Division of Cognitive and Behavioral Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
Neuropsychology. 2001 Apr;15(2):230-43.
Previous research has found that patients with probable Alzheimer's disease (AD) show lower levels of false recognition of semantic associates than do healthy older adults. To investigate whether this finding is attributable to semantic impairments in patients with AD, the authors examined false recognition of perceptually related novel objects with little semantic content in patients with AD and healthy older adults. By using corrected recognition scores to control for unrelated false alarms, it was found that patients with AD showed lower levels of both true and false recognition of novel objects than did older adults. These results suggest that the previous difference in false recognition of semantic associates observed between patients with AD and older adults is not entirely attributable to semantic memory deficits in patients with AD but may also involve poorly developed gist information in these patients.
先前的研究发现，患有可能的阿尔茨海默病（AD）的患者对语义关联的错误识别水平低于健康的老年人。为了研究这一发现是否归因于AD患者的语义损伤，作者检查了AD患者和健康老年人对语义内容很少的感知相关新物体的错误识别。通过使用校正后的识别分数来控制无关的误报，发现AD患者对新物体的正确和错误识别水平均低于老年人。这些结果表明，先前在AD患者和老年人之间观察到的对语义关联的错误识别差异并不完全归因于AD患者的语义记忆缺陷，还可能涉及这些患者中发展不完善的要点信息。
