Trenhaile T R, Killackey M A
Department of Obstetrics and Gynecology and Division of Gynecologic Oncology, St. Luke's-Roosevelt Hospital, New York, New York 10019, USA.
Obstet Gynecol. 2001 May;97(5 Pt 1):717-20. doi: 10.1016/s0029-7844(00)01225-4.
To describe five cases of primary pelvic non-Hodgkin's lymphoma, a rare gynecologic malignancy.
The charts of five women with primary pelvic non-Hodgkin's lymphoma were reviewed. Histologic classification was based on the Working Formulation, and staging was based on the Ann Arbor system. Disease status was monitored with physical examination and imaging studies.
During a 10-month period, five women were diagnosed with primary pelvic non-Hodgkin's lymphoma, including one parasacral, one uterine, one vaginal, and two ovarian tumors. Presentations included abdominal and pelvic pain, abdominal and pelvic mass, and abnormal vaginal bleeding. Treatment included combination chemotherapy, with or without radiation. Four patients were alive and disease free 20--33 months after therapy.
Primary pelvic non-Hodgkin's lymphoma may present like other more common gynecologic cancers. It should be considered in the differential diagnosis of gynecologic malignancy.
描述5例原发性盆腔非霍奇金淋巴瘤,一种罕见的妇科恶性肿瘤。
回顾了5例原发性盆腔非霍奇金淋巴瘤女性患者的病历。组织学分类依据工作分类法,分期依据Ann Arbor系统。通过体格检查和影像学检查监测疾病状态。
在10个月期间,5名女性被诊断为原发性盆腔非霍奇金淋巴瘤,包括1例骶旁、1例子宫、1例阴道和2例卵巢肿瘤。临床表现包括腹部和盆腔疼痛、腹部和盆腔肿块以及阴道异常出血。治疗包括联合化疗,可联合或不联合放疗。4例患者在治疗后20至33个月存活且无疾病。
原发性盆腔非霍奇金淋巴瘤可能表现得与其他更常见的妇科癌症相似。在妇科恶性肿瘤的鉴别诊断中应考虑到该病。